CAS 91421-42-0 appears in our catalog under these names: Rubitecan, 95%, Rubitecan, Rubitecan/ 98%, 9-Nitrocamptothecin, >98.0%(HPLC), Rubitecan 98%. Offered by: Combi-blocks, TRC, TargetMol, TCI, Biosynth. Available pack sizes: 100mg, 10mg, 2mg, 5mg, 25mg, 50mg, 250mg, 1g.
Rubitecan is a pyranoindolizinoquinoline that is camptothecin in which the hydrogen at position 9 has been replaced by a nitro group. It is a prodrug for 9-aminocamptothecin. It has a role as an antineoplastic agent, a prodrug and an EC 5.99.1.2 (DNA topoisomerase) inhibitor. It is a delta-lactone, a tertiary alcohol, a C-nitro compound, a pyranoindolizinoquinoline and a semisynthetic derivative.
Source: ChEBI
| Molecular formula | C20H15N3O6 |
|---|---|
| Molecular weight | 393.3 g/mol |
| IUPAC name | (19S)-19-ethyl-19-hydroxy-8-nitro-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione |
| InChIKey | VHXNKPBCCMUMSW-FQEVSTJZSA-N |
| SMILES | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC=C5[N+](=O)[O-])N=C4C3=C2)O |
Computed by PubChem (NCBI)