SAPANISERTIB, 99%
cas: 1224844-38-5 — see every product listed under this CAS number, including other names
SAPANISERTIB, 99% (CAS 1224844-38-5) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 50mg, 250mg. Offered by: Fluorochem.
| brand | Fluorochem |
|---|---|
| catalog number | F857996-10MG |
| cas | 1224844-38-5 |
| size | 10mg |
| availability | In Stock China |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Fluorochem | 10mg | 289.50 Pln | |
| Fluorochem | 50mg | 763.29 Pln | |
| Fluorochem | 250mg | 2382.51 Pln |
properties
| purity | 99% |
|---|---|
| dual use | No |
| currency | EUR |
| delivery time | 3-4 weeks |
| category | Odczynniki chemiczne |
Sapanisertib is a 1,3-benzoxazole substituted by amino and 4-amino-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl groups at positions 2 and 5, respectively. It is a ATP-competitive inhibitor of mTORC1 and mTORC2 that exhibits antineoplastic activity. It has a role as an antineoplastic agent, an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor, a mTOR inhibitor and an apoptosis inducer. It is an aromatic amine, a pyrazolopyrimidine, a primary amino compound and a member of 1,3-benzoxazoles.
Source: ChEBI
| Molecular formula | C15H15N7O |
|---|---|
| Molecular weight | 309.33 g/mol |
| IUPAC name | 5-(4-amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine |
| InChIKey | GYLDXIAOMVERTK-UHFFFAOYSA-N |
| SMILES | CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=C(C=C3)OC(=N4)N)N |
Computed by PubChem (NCBI)
Synonyms:
Sapanisertib, 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, 5-(4-amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine, 3-(2-Amino-1,3-benzoxazol-5-yl)-1-isopropyl-1H-pyrazolo(3,4-d)pyrimidin-4-amine, sapanisertibum, 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine, 5-(4-amino-1-propan-2-ylpyrazolo(3,4-d)pyrimidin-3-yl)-1,3-benzoxazol-2-amine, 5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine, Sapanisertib (MLN0128), 3-(2-aminobenzo[d]oxazol-5-yl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine