Products 1224844-38-5

CAS 1224844-38-5 appears in our catalog under these names: INK 128(MLN0128), 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine, >95% (HPLC), Sapanisertib/ 99.34% (existing batch purity), MLN0128, Sapanisertib. Offered by: GLPBio, TRC, TargetMol, Chemat, Biosynth. Available pack sizes: 5mg, 50mg, 1mg, 2mg, 10mg, 25mg, 100mg, 500mg.

INK 128(MLN0128)
GLPBio
  • size: 5mg, 10mg, 10mM (in 1ml dmso), 50mg
  • Variants: 4
from 685.97
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3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine, >95% (HPLC)
TRC
  • size: 50mg, 5mg
  • Variants: 2
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Sapanisertib/ 99.34% (existing batch purity)
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 8
from 412.42
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MLN0128
Chemat
  • size: 10mg, 1mg, 5mg
  • Variants: 3
from 1156.11
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Sapanisertib
Biosynth
  • size: 1000mg, 100mg, 250mg, 500mg
  • Variants: 4
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Sapanisertib 99%
Ambeed
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 8
from 264.69
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3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, 99%, 99%
Chemat
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 6
from 107.60
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Sapanisertib, 99.78%
MedChemExpress
  • size: 50 mg, 10mM/1mL, 10 mg, 25 mg
  • Variants: 6
from 579.76
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Sapanisertib (Standard)
MedChemExpress
  • size: 25 mg, 50 mg, 1 mg, 5 mg
  • Variants: 6
from 695.86
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SAPANISERTIB, 99%
Fluorochem
  • size: 10mg, 50mg, 250mg
  • Variants: 3
from 289.50
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Structural formula: {0} (CAS {1})

Sapanisertib is a 1,3-benzoxazole substituted by amino and 4-amino-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl groups at positions 2 and 5, respectively. It is a ATP-competitive inhibitor of mTORC1 and mTORC2 that exhibits antineoplastic activity. It has a role as an antineoplastic agent, an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor, a mTOR inhibitor and an apoptosis inducer. It is an aromatic amine, a pyrazolopyrimidine, a primary amino compound and a member of 1,3-benzoxazoles.

Source: ChEBI

Identity
Molecular formulaC15H15N7O
Molecular weight309.33 g/mol
IUPAC name5-(4-amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine
InChIKeyGYLDXIAOMVERTK-UHFFFAOYSA-N
SMILESCC(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=C(C=C3)OC(=N4)N)N

Computed by PubChem (NCBI)

Synonyms: Sapanisertib, 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, 5-(4-amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine, 3-(2-Amino-1,3-benzoxazol-5-yl)-1-isopropyl-1H-pyrazolo(3,4-d)pyrimidin-4-amine, sapanisertibum, 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine, 5-(4-amino-1-propan-2-ylpyrazolo(3,4-d)pyrimidin-3-yl)-1,3-benzoxazol-2-amine, 5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine, Sapanisertib (MLN0128), 3-(2-aminobenzo[d]oxazol-5-yl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine