SB-743921 (free base)
cas: 618430-39-0 — see every product listed under this CAS number, including other names
SB-743921 (free base) (CAS 618430-39-0) is a chemical reagent available from Chemat. Available pack sizes: Get quote. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-14661-Get quote |
| cas | 618430-39-0 |
| size | Get quote |
| availability | Get quote |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | Get quote | price on request |
properties
| delivery time | to confirm by Chemat |
|---|---|
| purity | no data |
SB-743921 is a chromone that is 4H-chromen-4-one substituted by (1R)-1-[(3-aminopropyl)(4-methylbenzoyl)amino]-2-methylpropyl, benzyl, and chloro groups at positions 2, 3, and 7, respectively. It is a potent inhibitor of kinesin spindle protein (Ki = 0.1 nM) and exhibits antineoplastic activity. It has a role as an antineoplastic agent, a microtubule-destabilising agent and an apoptosis inducer. It is a tertiary carboxamide, a member of benzamides, a member of benzenes, a member of chromones, a member of toluenes, an organochlorine compound and a primary amino compound.
Source: ChEBI
| Molecular formula | C31H33ClN2O3 |
|---|---|
| Molecular weight | 517.1 g/mol |
| IUPAC name | N-(3-aminopropyl)-N-[(1R)-1-(3-benzyl-7-chloro-4-oxochromen-2-yl)-2-methylpropyl]-4-methylbenzamide |
| InChIKey | PGXYIBJJCLWJST-MUUNZHRXSA-N |
| SMILES | CC1=CC=C(C=C1)C(=O)N(CCCN)[C@@H](C2=C(C(=O)C3=C(O2)C=C(C=C3)Cl)CC4=CC=CC=C4)C(C)C |
Computed by PubChem (NCBI)