Products 618430-39-0

CAS 618430-39-0 appears in our catalog under these names: SB-743921 free base, SB-743921 (free base). Offered by: TargetMol, MedChemExpress. Available pack sizes: 25mg, 50mg, 100mg, Get quote.

SB-743921 free base
TargetMol
  • size: 25mg, 50mg, 100mg
  • Variants: 3
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SB-743921 (free base)
MedChemExpress
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  • Variants: 1
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Structural formula: {0} (CAS {1})

SB-743921 is a chromone that is 4H-chromen-4-one substituted by (1R)-1-[(3-aminopropyl)(4-methylbenzoyl)amino]-2-methylpropyl, benzyl, and chloro groups at positions 2, 3, and 7, respectively. It is a potent inhibitor of kinesin spindle protein (Ki = 0.1 nM) and exhibits antineoplastic activity. It has a role as an antineoplastic agent, a microtubule-destabilising agent and an apoptosis inducer. It is a tertiary carboxamide, a member of benzamides, a member of benzenes, a member of chromones, a member of toluenes, an organochlorine compound and a primary amino compound.

Source: ChEBI

Identity
Molecular formulaC31H33ClN2O3
Molecular weight517.1 g/mol
IUPAC nameN-(3-aminopropyl)-N-[(1R)-1-(3-benzyl-7-chloro-4-oxochromen-2-yl)-2-methylpropyl]-4-methylbenzamide
InChIKeyPGXYIBJJCLWJST-MUUNZHRXSA-N
SMILESCC1=CC=C(C=C1)C(=O)N(CCCN)[C@@H](C2=C(C(=O)C3=C(O2)C=C(C=C3)Cl)CC4=CC=CC=C4)C(C)C

Computed by PubChem (NCBI)

Synonyms: KSP Inhibitor SB-743921, 618430-39-0 (free base), orb1699380
Related forms of this compound
N-(3-aminopropyl)-N-[(1R)-1-(3-benzyl-7-chloro-4-oxochromen-2-yl)-2-methylpropyl]-4-methylbenzamide C31H33ClN2O3