SIS3 – Smad3 inhibitor SIS3

cas: 521985-36-4 — see every product listed under this CAS number, including other names

SIS3 – Smad3 inhibitor SIS3 (CAS 521985-36-4) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 5mg, 10mM (in 1ml dmso). Offered by: GLPBio.

brandGLPBio
catalog numberGB40369-10
cas521985-36-4
size10mg
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Available pack sizes

brand size price
GLPBio 10mg 1701.64 Pln
GLPBio 5mg 1214.87 Pln
GLPBio 10mM (in 1ml dmso) 1294.43 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

SIS3 free base is an enamide resulting from the formal condensation of the amino group of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline with the carboxy group of (2E)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acrylic acid. It has a role as a Smad3 inhibitor. It is a tertiary carboxamide, a member of isoquinolines, a monocarboxylic acid amide, an aromatic ether, a pyrrolopyridine and an enamide. It is a conjugate base of a SIS3 free base(1+).

Source: ChEBI

Identity
Molecular formulaC28H27N3O3
Molecular weight453.5 g/mol
IUPAC name(E)-1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one
InChIKeyIJYPHMXWKKKHGT-VAWYXSNFSA-N
SMILESCN1C(=C(C2=C1N=CC=C2)/C=C/C(=O)N3CCC4=CC(=C(C=C4C3)OC)OC)C5=CC=CC=C5

Computed by PubChem (NCBI)

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