SMAD3 Inhibitor, SIS3

cas: 1009104-85-1 — see every product listed under this CAS number, including other names

SMAD3 Inhibitor, SIS3 (CAS 1009104-85-1) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 25mg, 5mg, 50mg. Offered by: GLPBio, Biosynth.

brandGLPBio
catalog numberGC44903-10
cas1009104-85-1
size10mg
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Available pack sizes

brand size price
GLPBio 10mg 1678.24 Pln
GLPBio 25mg 2731.35 Pln
GLPBio 5mg 1214.87 Pln
Biosynth 10mg price on request
Biosynth 5mg price on request
Biosynth 25mg price on request
Biosynth 50mg price on request

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

SIS3 free base is an enamide resulting from the formal condensation of the amino group of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline with the carboxy group of (2E)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acrylic acid. It has a role as a Smad3 inhibitor. It is a tertiary carboxamide, a member of isoquinolines, a monocarboxylic acid amide, an aromatic ether, a pyrrolopyridine and an enamide. It is a conjugate base of a SIS3 free base(1+).

Source: ChEBI

Identity
Molecular formulaC28H27N3O3
Molecular weight453.5 g/mol
IUPAC name(E)-1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one
InChIKeyIJYPHMXWKKKHGT-VAWYXSNFSA-N
SMILESCN1C(=C(C2=C1N=CC=C2)/C=C/C(=O)N3CCC4=CC(=C(C=C4C3)OC)OC)C5=CC=CC=C5

Computed by PubChem (NCBI)

Synonyms: Smad3 Inhibitor, SIS3, (E/Z)-SIS3 (free base), Smad3 Inhibitor, Smad3 inhibitor SIS3, starbld0007641, (E/Z)-SIS3 free base, orb1708519, s3552
Related forms of this compound
(E)-1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-[2-phenyl-1-(trideuteriomethyl)pyrrolo[2,3-b]pyridin-3-yl]prop-2-en-1-one C28H27N3O3
(E)-1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one C28H27N3O3
Isomers (same molecular formula)
methyl (2S)-2-acetamido-3-(1-tritylimidazol-4-yl)propanoate C28H27N3O3
[4-[(2S)-3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl]phenyl]methyl 2,4-dimethylbenzoate C28H27N3O3
[4-[(2R)-3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl]phenyl]methyl 2,4-dimethylbenzoate C28H27N3O3

Also listed as

1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one, 97%, 97% Chemat CAS 1009104-85-1
SMAD3 Inhibtor, SIS 3 TRC CAS 1009104-85-1
Smad3 Inhibitor, SIS3 Biosynth CAS 1009104-85-1
(E/Z)-SIS3 free base 97% Ambeed CAS 1009104-85-1
Smad3 Inhibitor, SIS3 1PC X 100MG Sigma-Aldrich CAS 1009104-85-1
Smad3 Inhibitor, SIS3 1PC X 1MG Sigma-Aldrich CAS 1009104-85-1
Smad3 Inhibitor, SIS3 1PC X 200MG Sigma-Aldrich CAS 1009104-85-1