CAS 192703-06-3 appears in our catalog under these names: SR 144528, SR144528/ 99.6% (existing batch purity), SR 144528, 5-(4-Chloro-3-methylphenyl)-1-(4-methylbenzyl)-N-((1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl)-1H-pyrazole-3-carboxamide, SR144528, 99.86%. Offered by: TRC, TargetMol, GLPBio, Biosynth, Chemat. Available pack sizes: 250mg, 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 2mg.
SR 144528 is a secondary carboxamide resulting from the formal condensation of the carboxy group of 5-(4-chloro-3-methylphenyl)-1-(4-methylbenzyl)-1H-pyrazole-3-carboxylic acid with the amino group of (1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-amine. A potent and selective cannabinoid receptor type 2 (CB2 receptor) inverse agonist (Ki = 0.6 nM). It has a role as an EC 2.3.1.26 (sterol O-acyltransferase) inhibitor and a CB2 receptor antagonist. It is a secondary carboxamide, a member of pyrazoles, a bridged compound and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C29H34ClN3O |
|---|---|
| Molecular weight | 476.1 g/mol |
| IUPAC name | 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethyl-2-bicyclo[2.2.1]heptanyl]pyrazole-3-carboxamide |
| InChIKey | SUGVYNSRNKFXQM-XRHWURSXSA-N |
| SMILES | CC1=CC=C(C=C1)CN2C(=CC(=N2)C(=O)N[C@H]3[C@]4(CC[C@H](C4)C3(C)C)C)C5=CC(=C(C=C5)Cl)C |
Computed by PubChem (NCBI)