Products 215543-92-3
CAS 215543-92-3 appears in our catalog under these names: 2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid, ≥98%, SU 5402, >95% (HPLC), SU 5402, SU 5402/ 99.08% (existing batch purity), SU 5402. Offered by: Fluorochem, TRC, GLPBio, TargetMol, Biosynth. Available pack sizes: 1mg, 5mg, 25mg, 10mg, 10mM (in 1ml dmso), 50mg, 100mg, 0,1g.
SU5402 is an oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is substituted by a 3-(2-carboxyethyl)-4-methyl-1H-pyrrol-2-yl group. It is an ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth factor receptor 1. It has a role as a fibroblast growth factor receptor antagonist. It is a monocarboxylic acid, a member of pyrroles and a member of oxindoles. It is functionally related to a 3-methyleneoxindole.
Source: ChEBI
| Molecular formula | C17H16N2O3 |
|---|---|
| Molecular weight | 296.32 g/mol |
| IUPAC name | 3-[4-methyl-2-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid |
| InChIKey | JNDVEAXZWJIOKB-JYRVWZFOSA-N |
| SMILES | CC1=CNC(=C1CCC(=O)O)/C=C\2/C3=CC=CC=C3NC2=O |
Computed by PubChem (NCBI)
Synonyms:
su5402, 3-[3-(2-Carboxyethyl)-4-methylpyrrol-2-methylidenyl]-2-indolinone, (Z)-3-(4-methyl-2-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid, 3-{[3-(2-carboxyethyl)-4-methylpyrrol-2-yl]methylene}-2-indolinone, 3-(4-methyl-2-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid, JNDVEAXZWJIOKB-JYRVWZFOSA-N, KDR Kinase Inhibitor, 5, orb1223187, compound 1 [PMID: 10602697]