Products 658084-23-2
CAS 658084-23-2 appears in our catalog under these names: SU11274/ 99.44% (existing batch purity), SU11274, SU 11274, SU11274 98%, SU11274, 99.02%. Offered by: TargetMol, GLPBio, Biosynth, Ambeed, MedChemExpress. Available pack sizes: 1mg, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg, 10mM (in 1ml dmso).
SU11274 is a member of the class of oxindoles that is 1,3-dihydro-2H-indol-2-one substituted by {3,5-dimethyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-2-yl}methylidene and N-(3-chlorophenyl)-N-methylmethanesulfonyl groups at positions 3 and 5, respectively. It is a potent ATP-competitive inhibitor of c-Met (IC50 = 20 nM) and exhibits antineoplastic activity. It has a role as an autophagy inducer, an antineoplastic agent, an apoptosis inducer and a c-Met tyrosine kinase inhibitor. It is a sulfonamide, a member of oxindoles, a N-acylpiperazine, a N-methylpiperazine, a pyrrolecarboxamide, an aromatic ketone, an olefinic compound and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C28H30ClN5O4S |
|---|---|
| Molecular weight | 568.1 g/mol |
| IUPAC name | (3Z)-N-(3-chlorophenyl)-3-[[3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl]methylidene]-N-methyl-2-oxo-1H-indole-5-sulfonamide |
| InChIKey | FPYJSJDOHRDAMT-KQWNVCNZSA-N |
| SMILES | CC1=C(NC(=C1C(=O)N2CCN(CC2)C)C)/C=C\3/C4=C(C=CC(=C4)S(=O)(=O)N(C)C5=CC(=CC=C5)Cl)NC3=O |
Computed by PubChem (NCBI)