Products 405060-95-9

CAS 405060-95-9 appears in our catalog under these names: Salubrinal, >95% (HPLC), Salubrinal/ 99.97% (existing batch purity), Salubrinal, Salubrinal , Salubrinal 99%. Offered by: TRC, TargetMol, GLPBio, Thermo Scientific (Alfa Aesar), Ambeed. Available pack sizes: 10mg, 25mg, 5mg, 2mg, 50mg, 100mg, 500mg, 1mg.

Salubrinal, >95% (HPLC)
TRC
  • size: 10mg, 25mg, 5mg
  • Variants: 3
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Salubrinal/ 99.97% (existing batch purity)
TargetMol
  • size: 2mg, 5mg, 10mg, 25mg
  • Variants: 7
from 419.13
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Salubrinal
GLPBio, Thermo Scientific (Alfa Aesar)
  • size: 1mg, 10mg, 100mg, 25mg
  • Variants: 9
from 512.79
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Salubrinal 99%
Ambeed
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 8
from 159.00
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(2E)-3-Phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-2-propenamide, 99%, 99%
Chemat
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 8
from 88.40
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Salubrinal, 99.58%
MedChemExpress
  • size: 10mM/1mL, 500 mg, 50 mg, 1 g
  • Variants: 9
from 463.66
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Salubrinal (Standard)
MedChemExpress
  • size: 25 mg, 100 mg, 50 mg, 10 mg
  • Variants: 5
from 886.26
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Salubrinal, 99%
Fluorochem
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 7
from 133.30
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Structural formula: {0} (CAS {1})

Salubrinal is a member of the class of quinolines that is a mixed aminal resulting from the formal condensation oftrichloroacetaldehyde with the amide nitrogen of trans-cinnamamide and the primary amino group of 1-quinolin-8-ylthiourea. It is a selective inhibitor of cellular complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit alpha (eIF2alpha). It is a secondary carboxamide, a member of quinolines, an aminal, an organochlorine compound and a member of thioureas. It is functionally related to a trichloroacetaldehyde and a trans-cinnamamide.

Source: ChEBI

Identity
Molecular formulaC21H17Cl3N4OS
Molecular weight479.8 g/mol
IUPAC name(E)-3-phenyl-N-[2,2,2-trichloro-1-(quinolin-8-ylcarbamothioylamino)ethyl]prop-2-enamide
InChIKeyLCOIAYJMPKXARU-VAWYXSNFSA-N
SMILESC1=CC=C(C=C1)/C=C/C(=O)NC(C(Cl)(Cl)Cl)NC(=S)NC2=CC=CC3=C2N=CC=C3

Computed by PubChem (NCBI)

Synonyms: salubrinal, N-(2,2,2-trichloro-1-(3-(quinolin-8-yl)thioureido)ethyl)cinnamamide, (E)-N-(2,2,2-Trichloro-1-(3-(quinolin-8-yl)thioureido)ethyl)cinnamamide, C21H17Cl3N4OS, Salubrinal?, orb1225105, orb1304594, LCOIAYJMPKXARU-VAWYXSNFSA-N
Related forms of this compound
(E)-3-phenyl-N-[2,2,2-trichloro-1-(quinolin-8-ylcarbamothioylamino)ethyl]prop-2-enamide C21H17Cl3N4OS