Products 149606-27-9

CAS 149606-27-9 appears in our catalog under these names: Soblidotin/ 97.48% (existing batch purity), Soblidotin (Auristatin PE), Soblidotin, Soblidotin, 99.29%. Offered by: TargetMol, GLPBio, Chemat, MedChemExpress. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 10mM (in 1ml dmso), 50mg, 100 mg, 1 mg.

Soblidotin/ 97.48% (existing batch purity)
TargetMol
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 4
from 910.49
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Soblidotin (Auristatin PE)
GLPBio
  • size: 1mg, 10mg, 10mM (in 1ml dmso), 25mg
  • Variants: 6
from 1018.28
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Soblidotin
Chemat
  • size: 1mg, 5mg, 10mg
  • Variants: 3
from 621.20
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Soblidotin, 99.29%
MedChemExpress
  • size: 100 mg, 1 mg, 50 mg, 10 mg
  • Variants: 6
from 793.38
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Structural formula: {0} (CAS {1})

Soblidotin is a tetrapeptide derivative of dolastatin 10. It is an inhibitor of tubulin polymerization which exhibits potent antitumor activity. It has a role as an antineoplastic agent, a microtubule-destabilising agent and an apoptosis inducer. It is functionally related to a L-valine and a 2-phenylethylamine.

Source: ChEBI

Identity
Molecular formulaC39H67N5O6
Molecular weight702.0 g/mol
IUPAC name(2S)-2-[[(2S)-2-(dimethylamino)-3-methylbutanoyl]amino]-N-[(3R,4S,5S)-3-methoxy-1-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-(2-phenylethylamino)propyl]pyrrolidin-1-yl]-5-methyl-1-oxoheptan-4-yl]-N,3-dimethylbutanamide
InChIKeyDZMVCVHATYROOS-ZBFGKEHZSA-N
SMILESCC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)NCCC2=CC=CC=C2)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C

Computed by PubChem (NCBI)

Synonyms: Soblidotin, Auristatin PE, Tzt-1027, Soblidotina, Soblidotine, Tzt 1027, soblidotinum, Soblidotin [INN], Auristatin PE;TZT-1027, Soblitodin