Sofosbuvir

cas: 1190307-88-0 — see every product listed under this CAS number, including other names

Sofosbuvir (CAS 1190307-88-0) is a chemical reagent available from Chemat. Available pack sizes: on request, 5g, 2g, 10g, 25g. Offered by: Chemat Brand, Biosynth.

brandChemat Brand
catalog numberULS055002
cas1190307-88-0
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
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Biosynth 2g price on request
Biosynth 10g price on request
Biosynth 25g price on request

properties

purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Sofosbuvir is a nucleotide conjugate that is used in combination with ledipasvir (under the trade name Harvoni) for the treatment of chronic hepatitis C genotype 1 infection. It has a role as an antiviral drug, a prodrug and a hepatitis C protease inhibitor. It is a phosphoramidate ester, an isopropyl ester, an organofluorine compound, a nucleotide conjugate and a L-alanyl ester. It is functionally related to a uridine 5'-monophosphate.

Source: ChEBI

Identity
Molecular formulaC22H29FN3O9P
Molecular weight529.5 g/mol
IUPAC namepropan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
InChIKeyTTZHDVOVKQGIBA-IQWMDFIBSA-N
SMILESC[C@@H](C(=O)OC(C)C)N[P@](=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3

Computed by PubChem (NCBI)

Synonyms: SOFOSBUVIR, SOVALDI, VOSEVI COMPONENT SOFOSBUVIR, EPCLUSA COMPONENT SOFOSBUVIR, HARVONI COMPONENT SOFOSBUVIR, sofosbuvirum, Sovaldi Access, Psi-7977, gs-7977, Sofosbuvir [USAN], Sofosbuvir [USAN:INN]
Related forms of this compound
propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate C22H29FN3O9P
propan-2-yl (2R)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate C22H29FN3O9P
propan-2-yl (2R)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate C22H29FN3O9P
propan-2-yl (2R)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate C22H29FN3O9P
1,1,1,3,3,3-hexadeuteriopropan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate C22H29FN3O9P
propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-(trideuterio(113C)methyl)oxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate C22H29FN3O9P
propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate C22H29FN3O9P
Isomers (same molecular formula)
propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-2-(hydroxymethyl)-4-methyloxolan-3-yl]oxy-phenoxyphosphoryl]amino]propanoate C22H29FN3O9P

Also listed as

Sofosbuvir/ 99.93% (existing batch purity) TargetMol CAS 1190307-88-0
PSI–7977 GLPBio CAS 1190307-88-0
Sofosbuvir - Bio-X â„¢ Biosynth CAS 1190307-88-0
Sofosbuvir, 98% Thermo Scientific (Acros) CAS 1190307-88-0
Sofosbuvir, 98.00% Chemat CAS 1190307-88-0
Sofosbuvir 99% Ambeed CAS 1190307-88-0
Sofosbuvir, 99%, 99% Chemat CAS 1190307-88-0
Sofosbuvir, 99.99% MedChemExpress CAS 1190307-88-0
Sofosbuvir (Standard), 99.99% MedChemExpress CAS 1190307-88-0
Sofosbuvir, min. 95 %, 1 g Roth CAS 1190307-88-0
Sofosbuvir, min. 95 %, 2 g Roth CAS 1190307-88-0
Sofosbuvir, min. 95 %, 5 g Roth CAS 1190307-88-0