Products 1190307-88-0

CAS 1190307-88-0 appears in our catalog under these names: Sofosbuvir, Sofosbuvir/ 99.93% (existing batch purity), PSI–7977, Sofosbuvir - Bio-X â„¢, Sofosbuvir, 98%. Offered by: Chemat Brand, TargetMol, GLPBio, Biosynth, Thermo Scientific (Acros). Available pack sizes: on request, 1g, 5mg, 10mg, 50mg, 100mg, 500mg, 10mM (in 1ml dmso).

Sofosbuvir
Chemat Brand, Biosynth
  • size: on request, 5g, 2g, 10g
  • Variants: 5
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Sofosbuvir/ 99.93% (existing batch purity)
TargetMol
  • size: 1g, 5mg, 10mg, 50mg
  • Variants: 6
from 478.94
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PSI–7977
GLPBio
  • size: 10mg, 100mg, 1g, 5mg
  • Variants: 7
from 536.19
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Sofosbuvir - Bio-X â„¢
Biosynth
  • size: 10mg
  • Variants: 1
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Sofosbuvir, 98%
Thermo Scientific (Acros)
  • size: 250MG
  • Variants: 1
from 1461.06
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Sofosbuvir, 98.00%
Chemat
  • size: 10mg, 25mg, 50mg
  • Variants: 3
from 1932.32
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Sofosbuvir 99%
Ambeed
  • size: 100g, 5mg, 10mg, 100mg
  • Variants: 8
from 175.69
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Sofosbuvir, 99%, 99%
Chemat
  • size: 5mg, 10mg, 250mg, 1g
  • Variants: 9
from 78.80
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Sofosbuvir, 99.99%
MedChemExpress
  • size: 50 mg, 10mM/1mL, 500 mg, 1 g
  • Variants: 7
from 384.71
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Sofosbuvir (Standard), 99.99%
MedChemExpress
  • size: 25 mg, 10 mg, 50 mg, 5 mg
  • Variants: 5
from 742.30
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Sofosbuvir, min. 95 %, 1 g
Roth
  • size: 1g
  • Variants: 1
from 1599.95
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Sofosbuvir, min. 95 %, 2 g
Roth
  • size: 2g
  • Variants: 1
from 1269.58
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Sofosbuvir, min. 95 %, 5 g
Roth
  • size: 5g
  • Variants: 1
from 1883.12
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Structural formula: {0} (CAS {1})

Sofosbuvir is a nucleotide conjugate that is used in combination with ledipasvir (under the trade name Harvoni) for the treatment of chronic hepatitis C genotype 1 infection. It has a role as an antiviral drug, a prodrug and a hepatitis C protease inhibitor. It is a phosphoramidate ester, an isopropyl ester, an organofluorine compound, a nucleotide conjugate and a L-alanyl ester. It is functionally related to a uridine 5'-monophosphate.

Source: ChEBI

Identity
Molecular formulaC22H29FN3O9P
Molecular weight529.5 g/mol
IUPAC namepropan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
InChIKeyTTZHDVOVKQGIBA-IQWMDFIBSA-N
SMILESC[C@@H](C(=O)OC(C)C)N[P@](=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3

Computed by PubChem (NCBI)

Synonyms: SOFOSBUVIR, SOVALDI, VOSEVI COMPONENT SOFOSBUVIR, EPCLUSA COMPONENT SOFOSBUVIR, HARVONI COMPONENT SOFOSBUVIR, sofosbuvirum, Sovaldi Access, Psi-7977, gs-7977, Sofosbuvir [USAN], Sofosbuvir [USAN:INN]
Related forms of this compound
propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate C22H29FN3O9P
propan-2-yl (2R)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate C22H29FN3O9P
propan-2-yl (2R)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate C22H29FN3O9P
propan-2-yl (2R)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate C22H29FN3O9P
1,1,1,3,3,3-hexadeuteriopropan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate C22H29FN3O9P
propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-(trideuterio(113C)methyl)oxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate C22H29FN3O9P
propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate C22H29FN3O9P
Isomers (same molecular formula)
propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-2-(hydroxymethyl)-4-methyloxolan-3-yl]oxy-phenoxyphosphoryl]amino]propanoate C22H29FN3O9P