Products 1218778-77-8

CAS 1218778-77-8 appears in our catalog under these names: LDE225 Diphosphate, Sonidegib diphosphate/ 99.86% (existing batch purity), rel-N-(6-((2R,6S)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide bis(phosphate), Sonidegib (diphosphate), 99.97%. Offered by: GLPBio, TargetMol, Chemat, MedChemExpress. Available pack sizes: 10mg, 100mg, 1g, 5mg, 10mM (in 1ml dmso), 50mg, 500mg, 25mg.

LDE225 Diphosphate
GLPBio
  • size: 10mg, 100mg, 1g, 5mg
  • Variants: 7
from 578.32
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Sonidegib diphosphate/ 99.86% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 5
from 465.53
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rel-N-(6-((2R,6S)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide bis(phosphate)
Chemat
  • size: 5mg, 10mg, 50mg, 100mg
  • Variants: 5
from 338.00
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Sonidegib (diphosphate), 99.97%
MedChemExpress
  • size: 100 mg, 5 mg, 50 mg, 10 mg
  • Variants: 5
from 384.71
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Structural formula: {0} (CAS {1})

Sonidegib phosphate is a phosphate salt obtained by reaction sonidegib with two equivalent of phosphoric acid. Used for treatment of locally advanced basal cell carcinoma. It has a role as a Hedgehog signaling pathway inhibitor, an antineoplastic agent and a SMO receptor antagonist. It contains a sonidegib.

Source: ChEBI

Identity
Molecular formulaC26H32F3N3O11P2
Molecular weight681.5 g/mol
IUPAC nameN-[6-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-3-pyridinyl]-2-methyl-3-[4-(trifluoromethoxy)phenyl]benzamide;phosphoric acid
InChIKeyRWIVSVMMGFFZIJ-VWDRLOGHSA-N
SMILESC[C@@H]1CN(C[C@@H](O1)C)C2=NC=C(C=C2)NC(=O)C3=CC=CC(=C3C)C4=CC=C(C=C4)OC(F)(F)F.OP(=O)(O)O.OP(=O)(O)O

Computed by PubChem (NCBI)

Synonyms: Sonidegib phosphate, sonidegib diphosphate, Erismodegib phosphate, sonidegib bisphosphate, NVP-LDE225 Diphosphate, Sonidegib phosphate [USAN:INN], Sonidegib (diphosphate), Sonidegib phosphate (USAN), SONIDEGIB PHOSPHATE [USAN], Erismodegib (diphosphate)