Sotrastaurin (AEB071)
cas: 425637-18-9 — see every product listed under this CAS number, including other names
Sotrastaurin (AEB071) (CAS 425637-18-9) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 25mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC15520-10 |
| cas | 425637-18-9 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 1055.73 Pln | |
| GLPBio | 25mg | 2085.44 Pln | |
| GLPBio | 5mg | 812.34 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 859.15 Pln | |
| GLPBio | 50mg | 3166.63 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Sotrastaurin is a member of the class of maleimides that is maleimide which is substituted at position 3 by an indol-3-yl group and at position 4 by a quinazolin-4-yl group, which in turn is substituted at position 2 by a 4-methylpiperazin-1-yl group. It is a potent and selective inhibitor of protein kinase C and has been investigated as an immunosuppresant in renal transplant patients. It has a role as an anticoronaviral agent, an immunosuppressive agent and an EC 2.7.11.13 (protein kinase C) inhibitor. It is a member of indoles, a member of quinazolines, a N-alkylpiperazine, a N-arylpiperazine and a member of maleimides.
Source: ChEBI
| Molecular formula | C25H22N6O2 |
|---|---|
| Molecular weight | 438.5 g/mol |
| IUPAC name | 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione |
| InChIKey | OAVGBZOFDPFGPJ-UHFFFAOYSA-N |
| SMILES | CN1CCN(CC1)C2=NC3=CC=CC=C3C(=N2)C4=C(C(=O)NC4=O)C5=CNC6=CC=CC=C65 |
Computed by PubChem (NCBI)
Synonyms:
Sotrastaurin, sotrastaurina, sotrastaurine, sotrastaurinum, 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione, 3-(1H-indol-3-yl)-4-(2-(4-methylpiperazin-1-yl)quinazolin-4-yl)pyrrole-2,5-dione, Sotrastaurin (AEB071), Sotrastaurin [USAN], SOTRASTAURIN [WHO-DD], Sotrastaurin [USAN:INN]