Products 2649467-58-1
CAS 2649467-58-1 appears in our catalog under these names: Suzetrigine, Suzetrigine/ 98.87% (existing batch purity), 4-[[[(2R,3S,4S,5R)-3-(3,4-Difluoro-2-methoxyphenyl)tetrahydro-4,5-dimethyl-5-(trifluoromethyl)-2-furanyl]carbonyl]amino]-2-pyridinecarboxamide, 98%, 98%, Suzetrigine, 99.96%, Suzetrigine, 98%. Offered by: GLPBio, TargetMol, Biosynth, Chemat, MedChemExpress. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 250mg, 100mg, 1g.
Suzetrigine is a member of the class of oxolanes that is oxolane substituted by 4-aminoacyl-pyridine-2-carboxamide, 3,4-difluoro-2-methoxyphenyl, methyl, and trifluoromethyl groups at positions 2, 3, 4, 5, and 5, respectively (the 2R,3S,4S,5R-stereoisomer). It is a selective blocker of the NaV 1.8 voltage-gated sodium channel and has been approved for the treatment of moderate to severe acute pain in adults. It has a role as a non-narcotic analgesic and a voltage-gated sodium channel blocker. It is a primary carboxamide, a secondary carboxamide, a monomethoxybenzene, a pyridinecarboxamide, a member of oxolanes and a difluorobenzene.
Source: ChEBI
| Molecular formula | C21H20F5N3O4 |
|---|---|
| Molecular weight | 473.4 g/mol |
| IUPAC name | 4-[[(2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)oxolane-2-carbonyl]amino]pyridine-2-carboxamide |
| InChIKey | XSQUJFKRXZMOKA-PAFIKIDNSA-N |
| SMILES | C[C@H]1[C@H]([C@@H](O[C@@]1(C)C(F)(F)F)C(=O)NC2=CC(=NC=C2)C(=O)N)C3=C(C(=C(C=C3)F)F)OC |
Computed by PubChem (NCBI)