Tanespimycin, 99.01%

cas: 75747-14-7 — see every product listed under this CAS number, including other names

Tanespimycin, 99.01% (CAS 75747-14-7) is a chemical reagent available from Chemat. Available pack sizes: 5 mg, 200 mg, 10 mg, 25 mg, 50 mg, 10mM/1mL, 100 mg. Offered by: MedChemExpress.

brand	MedChemExpress
catalog number	HY-10211-5 mg
cas	75747-14-7
size	5 mg
availability	In stock

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Available pack sizes

brand	size	price
MedChemExpress	5 mg	342.91 Pln
MedChemExpress	200 mg	2135.50 Pln
MedChemExpress	10 mg	463.66 Pln
MedChemExpress	25 mg	695.86 Pln
MedChemExpress	50 mg	1081.31 Pln
MedChemExpress	10mM/1mL	500.81 Pln
MedChemExpress	100 mg	1559.64 Pln

properties

delivery time	1-2 weeks
purity	99.01%

Tanespimycin is a 19-membered macrocyle that is geldanamycin in which the methoxy substituent attached to the benzoquinone moiety has been replaced by an allylamino group. It is a potent inhibitor of heat shock protein 90 (Hsp90). A less toxic analogue than geldanamycin, it induces apoptosis and displays antitumour effects. It has a role as an antineoplastic agent, a Hsp90 inhibitor and an apoptosis inducer. It is a member of 1,4-benzoquinones, an ansamycin, a carbamate ester, an organic heterobicyclic compound and a secondary amino compound. It is functionally related to a geldanamycin.

Source: ChEBI

Identity
Molecular formula	C₃₁H₄₃N₃O₈
Molecular weight	585.7 g/mol
IUPAC name	[(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-enylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate
InChIKey	AYUNIORJHRXIBJ-TXHRRWQRSA-N
SMILES	C[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C\C=C(\C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)/C)OC)OC(=O)N)\C)C)O)OC