Products 897016-82-9
CAS 897016-82-9 appears in our catalog under these names: KX2-391, KX2–391, Tirbanibulin/ 99.67% (existing batch purity), Tirbanibulin 98+%, N-Benzyl-2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetamide, 98+%, 98+%. Offered by: TRC, GLPBio, TargetMol, Ambeed, Chemat. Available pack sizes: 250mg, 10mg, 5mg, 50mg, 2mg, 25mg, 100mg, 1mg.
Tirbanibulin is a member of the class of pyridines that is pyridine substituted by 2-(benzylamino)-2-oxoethyl and 4-[2-(morpholin-4-yl)ethoxy]phenyl groups at positions 2 and 5, respectively. It is a dual inhibitor of Src kinase and tubulin and approved by the FDA for the topical treatment of actinic keratosis on the face or scalp. It has a role as an antineoplastic agent, a microtubule-destabilising agent, an apoptosis inducer and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a secondary carboxamide, a member of pyridines, an aromatic ether and a member of morpholines.
Source: ChEBI
| Molecular formula | C26H29N3O3 |
|---|---|
| Molecular weight | 431.5 g/mol |
| IUPAC name | N-benzyl-2-[5-[4-(2-morpholin-4-ylethoxy)phenyl]-2-pyridinyl]acetamide |
| InChIKey | HUNGUWOZPQBXGX-UHFFFAOYSA-N |
| SMILES | C1COCCN1CCOC2=CC=C(C=C2)C3=CN=C(C=C3)CC(=O)NCC4=CC=CC=C4 |
Computed by PubChem (NCBI)
Synonyms:
Tirbanibulin, Klisyri, N-benzyl-2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetamide, tirbanibulina, tirbanibuline, N-benzyl-2-(5-{4-[2-(morpholin-4-yl)ethoxy]phenyl}pyridin-2-yl)acetamide, 2-Pyridineacetamide, 5-(4-(2-(4-morpholinyl)ethoxy)phenyl)-n-(phenylmethyl)-, tirbanibulinum, N-benzyl-2-(5-(4-(2-(morpholin-4-yl)ethoxy)phenyl)pyridin-2-yl)acetamide, 2-(5-(4-(2-morpholin-4-ylethoxy)phenyl)pyridin-2-yl)-N-(phenylmethyl)acetamide