cas: 475108-18-0 — see every product listed under this CAS number, including other names
Tivozanib, 98%, 98% (CAS 475108-18-0) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 50mg, 100mg, 250mg, 1g. Offered by: Chemat.
| brand | Chemat |
|---|---|
| catalog number | Ch1181FI-1mg |
| cas | 475108-18-0 |
| size | 1mg |
| availability | 5g |
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| brand | size | price | |
|---|---|---|---|
| Chemat | 1mg | 136.40 Pln | |
| Chemat | 5mg | 150.80 Pln | |
| Chemat | 50mg | 587.60 Pln | |
| Chemat | 100mg | 822.80 Pln | |
| Chemat | 250mg | 1485.20 Pln | |
| Chemat | 1g | 3899.60 Pln |
| purity | 98% |
|---|---|
| delivery time | 3 weeks |
Tivozanib is a member of the class of quinolines that is 6,7-dimethoxyquinoline substituted by a 3-chloro-4-{[(5-methyl-1,2-oxazol-3-yl)carbamoyl]amino}phenoxy group at position 4. It is a potent and selective inhibitor of VEGF receptor tyrosine kinases and was previously in clinical development for the treatment of metastatic renal cell carcinoma. It has a role as an antineoplastic agent, a vascular endothelial growth factor receptor antagonist and an apoptosis inducer. It is a member of phenylureas, a member of quinolines, an aromatic ether, a member of isoxazoles and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C22H19ClN4O5 |
|---|---|
| Molecular weight | 454.9 g/mol |
| IUPAC name | 1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(5-methyl-1,2-oxazol-3-yl)urea |
| InChIKey | SPMVMDHWKHCIDT-UHFFFAOYSA-N |
| SMILES | CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl |
Computed by PubChem (NCBI)