Trofinetide

cas: 853400-76-7 — see every product listed under this CAS number, including other names

Trofinetide (CAS 853400-76-7) is a chemical reagent available from Chemat. Available pack sizes: on request, 100mg, 50mg, 250mg, 500mg. Offered by: Chemat Brand, Biosynth.

brandChemat Brand
catalog numberULT418001
cas853400-76-7
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
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Available pack sizes

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Chemat Brand on request price on request
Biosynth 100mg price on request
Biosynth 50mg price on request
Biosynth 250mg price on request
Biosynth 500mg price on request

properties

purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Trofinetide is a tripeptide comprising of glycine, 2-methyl-L-proline, and L-glutamic acid joined in sequence by peptide linkages. It is the first and only treatment approved by the FDA specifically indicated for Rett syndrome in adults and pediatric patients two years of age and older. It has a role as a neuroprotective agent and an anti-inflammatory agent. It is a secondary carboxamide, a tertiary carboxamide, a dicarboxylic acid, a pyrrolidinecarboxamide, a tripeptide and a primary amino compound. It is functionally related to a glycine and a L-glutamic acid.

Source: ChEBI

Identity
Molecular formulaC13H21N3O6
Molecular weight315.32 g/mol
IUPAC name(2S)-2-[[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidine-2-carbonyl]amino]pentanedioic acid
InChIKeyBUSXWGRAOZQTEY-SDBXPKJASA-N
SMILESC[C@]1(CCCN1C(=O)CN)C(=O)N[C@@H](CCC(=O)O)C(=O)O

Computed by PubChem (NCBI)

Synonyms: Trofinetide, DAYBUE, trofinetida, L-Glutamic acid, glycyl-2-methyl-L-prolyl-, trofinetidum, Glycyl-2-methyl-L-prolyl-L-glutamic acid, Trofinetide [INN], Trofinetide(NNZ2566), Trofinetide [USAN], glycyl-L-2-methylprolyl-L-glutamic acid
Isomers (same molecular formula)
4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidin-2-one C13H21N3O6

Also listed as

Trofinetide (>90%) TRC CAS 853400-76-7
Trofinetide/ 98.7% (existing batch purity) TargetMol CAS 853400-76-7
Trofinetide (NNZ–2566) GLPBio CAS 853400-76-7
Trofinetide 99% Ambeed CAS 853400-76-7
Glycyl-2-methyl-L-prolyl-L-glutamic acid, 99%, 99% Chemat CAS 853400-76-7
Trofinetide, 99.90% MedChemExpress CAS 853400-76-7