Products 853400-76-7
CAS 853400-76-7 appears in our catalog under these names: Trofinetide, Trofinetide (>90%), Trofinetide/ 98.7% (existing batch purity), Trofinetide (NNZ–2566), Trofinetide 99%. Offered by: Chemat Brand, TRC, TargetMol, GLPBio, Biosynth. Available pack sizes: on request, 0,5mg, 2,5mg, 5mg, 1mg, 10mg, 25mg, 50mg.
Trofinetide is a tripeptide comprising of glycine, 2-methyl-L-proline, and L-glutamic acid joined in sequence by peptide linkages. It is the first and only treatment approved by the FDA specifically indicated for Rett syndrome in adults and pediatric patients two years of age and older. It has a role as a neuroprotective agent and an anti-inflammatory agent. It is a secondary carboxamide, a tertiary carboxamide, a dicarboxylic acid, a pyrrolidinecarboxamide, a tripeptide and a primary amino compound. It is functionally related to a glycine and a L-glutamic acid.
Source: ChEBI
| Molecular formula | C13H21N3O6 |
|---|---|
| Molecular weight | 315.32 g/mol |
| IUPAC name | (2S)-2-[[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidine-2-carbonyl]amino]pentanedioic acid |
| InChIKey | BUSXWGRAOZQTEY-SDBXPKJASA-N |
| SMILES | C[C@]1(CCCN1C(=O)CN)C(=O)N[C@@H](CCC(=O)O)C(=O)O |
Computed by PubChem (NCBI)