Products 1481677-78-4

CAS 1481677-78-4 appears in our catalog under these names: UNC 0642, UNC0642/ 98.75% (existing batch purity), UNC0642 99%, UNC0642, 99.86%, UNC0642 (Standard). Offered by: GLPBio, TargetMol, Ambeed, MedChemExpress, Chemat. Available pack sizes: 10mg, 10mM (in 1ml dmso), 50mg, 1mg, 2mg, 5mg, 25mg, 100mg.

UNC 0642
GLPBio
  • size: 10mg, 10mM (in 1ml dmso), 50mg
  • Variants: 3
from 817.02
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UNC0642/ 98.75% (existing batch purity)
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 8
from 412.42
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UNC0642 99%
Ambeed
  • size: 1mg, 5mg, 10mg, 50mg
  • Variants: 5
from 303.62
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UNC0642, 99.86%
MedChemExpress
  • size: 25 mg, 10 mg, 50 mg, 5 mg
  • Variants: 7
from 361.49
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UNC0642 (Standard)
MedChemExpress
  • size: 10 mg, 25 mg, 50 mg, 100 mg
  • Variants: 5
from 1308.86
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UNC0642, 99%, 99%
Chemat
  • size: 1mg, 5mg, 10mg
  • Variants: 3
from 189.20
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2-(4,4-Difluoropiperidin-1-yl)-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine, 99%
Fluorochem
  • size: 1mg, 5mg, 10mg
  • Variants: 3
from 331.15
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Structural formula: {0} (CAS {1})

UNC0642 is a member of the class of quinazolines that is quinazoline substituted by 4,4-difluoropiperidin-1-yl, [1-(propan-2-yl)piperidin-4-yl]amino, methoxy, and 3-(pyrrolidin-1-yl)propoxy groups at positions 2, 4, 6 and 7, respectively. It is a potent inhibitor of histone methyltransferases G9a and GLP (IC50 = <2.5 nM). It has a role as an antineoplastic agent and an apoptosis inducer. It is an aromatic ether, an organofluorine compound, a member of pyrrolidines, a member of quinazolines, an aminopiperidine, a secondary amino compound and a tertiary amino compound.

Source: ChEBI

Identity
Molecular formulaC29H44F2N6O2
Molecular weight546.7 g/mol
IUPAC name2-(4,4-difluoropiperidin-1-yl)-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
InChIKeyRNAMYOYQYRYFQY-UHFFFAOYSA-N
SMILESCC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)N5CCC(CC5)(F)F

Computed by PubChem (NCBI)

Synonyms: orb1223285, orb1303097, RNAMYOYQYRYFQY-UHFFFAOYSA-N, s7230