cas: 67469-78-7 — see every product listed under this CAS number, including other names
Vanoxerine dihydrochloride (CAS 67469-78-7) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 25mg, 50mg, 100mg, 5mg, 10mM (in 1ml dmso). Offered by: TargetMol, GLPBio.
| brand | TargetMol |
|---|---|
| catalog number | T7153-10mg |
| cas | 67469-78-7 |
| size | 10mg |
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| brand | size | price | |
|---|---|---|---|
| TargetMol | 10mg | 472.23 Pln | |
| TargetMol | 25mg | 691.36 Pln | |
| TargetMol | 50mg | 970.30 Pln | |
| TargetMol | 100mg | 1329.18 Pln | |
| GLPBio | 10mg | 583.00 Pln | |
| GLPBio | 5mg | 531.51 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 550.23 Pln | |
| GLPBio | 50mg | 831.06 Pln |
| purity | No data |
|---|---|
| delivery time | approx. 15 days |
Vanoxerine dihydrochloride is a hydrochloride salt that is obtained by reaction of vanoxerine with two equivalents of hydrogen chloride. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration. It has a role as a dopamine uptake inhibitor. It contains a vanoxerine(2+).
Source: ChEBI
| Molecular formula | C28H34Cl2F2N2O |
|---|---|
| Molecular weight | 523.5 g/mol |
| IUPAC name | 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine;dihydrochloride |
| InChIKey | MIBSKSYCRFWIRU-UHFFFAOYSA-N |
| SMILES | C1CN(CCN1CCCC2=CC=CC=C2)CCOC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F.Cl.Cl |
Computed by PubChem (NCBI)