Vanoxerine

cas: 67469-69-6 — see every product listed under this CAS number, including other names

Vanoxerine (CAS 67469-69-6) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 25mg, 50mg, Get quote. Offered by: GLPBio, MedChemExpress.

brandGLPBio
catalog numberGC13322-10
cas67469-69-6
size10mg
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Available pack sizes

brand size price
GLPBio 10mg 573.64 Pln
GLPBio 25mg 742.14 Pln
GLPBio 50mg 1027.65 Pln
MedChemExpress Get quote price on request

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Vanoxerine is an N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration. It has a role as a dopamine uptake inhibitor. It is an ether, an organofluorine compound, a N-alkylpiperazine and a tertiary amino compound. It is a conjugate base of a vanoxerine(2+).

Source: ChEBI

Identity
Molecular formulaC28H32F2N2O
Molecular weight450.6 g/mol
IUPAC name1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine
InChIKeyNAUWTFJOPJWYOT-UHFFFAOYSA-N
SMILESC1CN(CCN1CCCC2=CC=CC=C2)CCOC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F

Computed by PubChem (NCBI)

Synonyms: Vanoxerine, Gbr 12909, Vanoxerina, Vanoxerinum, Vanoxeamine, 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine, 1-(2-(Bis(p-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)piperazine, 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine, 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)piperazine, 1-(2 (bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)piperazine