Products 67469-69-6

CAS 67469-69-6 is the registry number for Vanoxerine. Offered by: GLPBio, MedChemExpress. Available pack sizes: 10mg, 25mg, 50mg, Get quote.

Vanoxerine
GLPBio, MedChemExpress
  • size: 10mg, 25mg, 50mg, Get quote
  • Variants: 4
from 573.64
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Structural formula: {0} (CAS {1})

Vanoxerine is an N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration. It has a role as a dopamine uptake inhibitor. It is an ether, an organofluorine compound, a N-alkylpiperazine and a tertiary amino compound. It is a conjugate base of a vanoxerine(2+).

Source: ChEBI

Identity
Molecular formulaC28H32F2N2O
Molecular weight450.6 g/mol
IUPAC name1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine
InChIKeyNAUWTFJOPJWYOT-UHFFFAOYSA-N
SMILESC1CN(CCN1CCCC2=CC=CC=C2)CCOC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F

Computed by PubChem (NCBI)

Synonyms: Vanoxerine, Gbr 12909, Vanoxerina, Vanoxerinum, Vanoxeamine, 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine, 1-(2-(Bis(p-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)piperazine, 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine, 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)piperazine, 1-(2 (bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)piperazine