Products 172732-68-2
CAS 172732-68-2 appears in our catalog under these names: 2-((3-(2-Amino-2-oxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl)oxy)Acetic Acid, Varespladib, 95%, Varespladib, 98%, Varespladib/ 98%, Varespladib (LY315920). Offered by: TRC, Combi-blocks, AmBeed, TargetMol, GLPBio. Available pack sizes: 100mg, 10mg, 1mg, 5mg, 25mg, 50mg, 250mg, 1g.
Varespladib is a member of the class of indoles that is 1H-indole substituted by benzyl, ethyl, oxamoyl, and carboxymethoxy groups at positions 1, 2, 3, and 4, respectively. It is an oral secretory phospholipase A2 inhibitor and exhibits anti-inflammatory effects. It has a role as an anti-inflammatory drug, an antidote and an EC 3.1.1.4 (phospholipase A2) inhibitor. It is a primary carboxamide, a member of benzenes, a member of indoles, a monocarboxylic acid, an aromatic ether and a dicarboxylic acid monoamide. It is a conjugate acid of a varespladib(1-).
Source: ChEBI
| Molecular formula | C21H20N2O5 |
|---|---|
| Molecular weight | 380.4 g/mol |
| IUPAC name | 2-(1-benzyl-2-ethyl-3-oxamoylindol-4-yl)oxyacetic acid |
| InChIKey | BHLXTPHDSZUFHR-UHFFFAOYSA-N |
| SMILES | CCC1=C(C2=C(N1CC3=CC=CC=C3)C=CC=C2OCC(=O)O)C(=O)C(=O)N |
Computed by PubChem (NCBI)
Synonyms:
Varespladib, VAREPLADIB, varespladibum, ({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic acid, 2-(1-benzyl-2-ethyl-3-oxamoylindol-4-yl)oxyacetic acid, 2-{[1-benzyl-3-(carbamoylcarbonyl)-2-ethyl-1H-indol-4-yl]oxy}acetic acid, ((3-(aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl)oxy)acetate, 2-((1-benzyl-3-(carbamoylcarbonyl)-2-ethyl-1H-indol-4-yl)oxy)acetic acid, Varespladib (LY315920), Varespladib [USAN]