Vincristine

cas: 57-22-7 — see every product listed under this CAS number, including other names

Vincristine (CAS 57-22-7) is a chemical reagent available from Chemat. Available pack sizes: on request, 1mg, 10mg, 20mg, 5mg, 0,002g, 0,001g, 0,005g. Offered by: Chemat Brand, GLPBio, Biosynth.

brandChemat Brand
catalog numberULV191
cas57-22-7
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
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Available pack sizes

brand size price
Chemat Brand on request price on request
GLPBio 1mg 583.00 Pln
GLPBio 10mg 891.91 Pln
GLPBio 20mg 1271.03 Pln
GLPBio 5mg 700.01 Pln
Biosynth 0,002g price on request
Biosynth 0,001g price on request
Biosynth 0,005g price on request
Biosynth 0,025g price on request
Biosynth 0,01g price on request

properties

purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat

Vincristine is a vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer. It has a role as a drug, an antineoplastic agent, a tubulin modulator, a microtubule-destabilising agent and a plant metabolite. It is a member of formamides, a methyl ester, a tertiary alcohol, a vinca alkaloid, an organic heterotetracyclic compound, an organic heteropentacyclic compound, an acetate ester and a tertiary amino compound. It is a conjugate base of a vincristine(2+). It derives from a hydride of a vincaleukoblastine.

Source: ChEBI

Identity
Molecular formulaC46H56N4O10
Molecular weight825.0 g/mol
IUPAC namemethyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate
InChIKeyOGWKCGZFUXNPDA-XQKSVPLYSA-N
SMILESCC[C@@]1(C[C@@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O

Computed by PubChem (NCBI)

Synonyms: vincristine, 22-Oxovincaleukoblastine, Leurocristine, Vinkristin, Vincrystine, Vincristina, leucristine, vincristin, Tecnocris, Onco TCS
Related forms of this compound
methyl (1R,9R,10S,11R,12R,19R)-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-11-(2,2,2-trideuterioacetyl)oxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate C46H56N4O10

Also listed as

Vincristine/ 100% TargetMol CAS 57-22-7
Vincristine, 98.60% MedChemExpress CAS 57-22-7