CAS 57-22-7 appears in our catalog under these names: Vincristine, Vincristine/ 100%, Vincristine, 98.60%. Offered by: Chemat Brand, TargetMol, GLPBio, Biosynth, MedChemExpress. Available pack sizes: on request, 20mg, 1mg, 10mg, 5mg, 0,002g, 0,001g, 0,005g.
Vincristine is a vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer. It has a role as a drug, an antineoplastic agent, a tubulin modulator, a microtubule-destabilising agent and a plant metabolite. It is a member of formamides, a methyl ester, a tertiary alcohol, a vinca alkaloid, an organic heterotetracyclic compound, an organic heteropentacyclic compound, an acetate ester and a tertiary amino compound. It is a conjugate base of a vincristine(2+). It derives from a hydride of a vincaleukoblastine.
Source: ChEBI
| Molecular formula | C46H56N4O10 |
|---|---|
| Molecular weight | 825.0 g/mol |
| IUPAC name | methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate |
| InChIKey | OGWKCGZFUXNPDA-XQKSVPLYSA-N |
| SMILES | CC[C@@]1(C[C@@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O |
Computed by PubChem (NCBI)