Voreloxin

cas: 175414-77-4 — see every product listed under this CAS number, including other names

Voreloxin (CAS 175414-77-4) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 25mg, 5mg, 10mM (in 1ml dmso), 1mg, 2mg, 50mg, 100mg. Offered by: GLPBio, TargetMol, Biosynth, Chemat.

brandGLPBio
catalog numberGC13544-10
cas175414-77-4
size10mg
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Available pack sizes

brand size price
GLPBio 10mg 1500.38 Pln
GLPBio 25mg 2698.58 Pln
GLPBio 5mg 1060.41 Pln
GLPBio 10mM (in 1ml dmso) 1266.35 Pln
TargetMol 1mg 970.30 Pln
TargetMol 5mg 2657.36 Pln
TargetMol 25mg 9536.98 Pln
Biosynth 2mg price on request
Biosynth 5mg price on request
Biosynth 10mg price on request
Biosynth 25mg price on request
Chemat 1mg 419.60 Pln
Chemat 5mg 1058.00 Pln
Chemat 10mg 1653.20 Pln
Chemat 25mg 3275.60 Pln
Chemat 50mg 5205.20 Pln
Chemat 100mg 8291.60 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Vosaroxin is a 1,8-naphthyridine derivative that is 1,8-naphthyridin-4(1H)-one substituted by 1,3-thiazol-2-yl, carboxy, and (3S,4S)-3-methoxy-4-(methylamino)pyrrolidin-1-yl groups at positions 1, 3, and 7, respectively. It targets topoisomerase II and induces site-selective double-strand breaks in DNA, leading to apoptosis in cancer cells. It has a role as a radiosensitizing agent, a topoisomerase II inhibitor, an intercalator, an antineoplastic agent and an apoptosis inducer. It is a quinolone, a monocarboxylic acid, an ether, a member of pyrrolidines, a member of 1,3-thiazoles, a cyclic ketone, a secondary amino compound and a 1,8-naphthyridine derivative.

Source: ChEBI

Identity
Molecular formulaC18H19N5O4S
Molecular weight401.4 g/mol
IUPAC name7-[(3S,4S)-3-methoxy-4-(methylamino)pyrrolidin-1-yl]-4-oxo-1-(1,3-thiazol-2-yl)-1,8-naphthyridine-3-carboxylic acid
InChIKeyXZAFZXJXZHRNAQ-STQMWFEESA-N
SMILESCN[C@H]1CN(C[C@@H]1OC)C2=NC3=C(C=C2)C(=O)C(=CN3C4=NC=CS4)C(=O)O

Computed by PubChem (NCBI)

Synonyms: Voreloxin, vosaroxin, vosaroxina, vosaroxine, vosaroxinum, Vosaroxin (USAN), Vosaroxin [USAN], Quinprezo, Vosaroxin [USAN:INN], Voreloxin?

Also listed as

Voreloxin, 99.85% MedChemExpress CAS 175414-77-4
Voreloxin, min. 95 %, 2 mg Roth CAS 175414-77-4
Voreloxin, min. 95 %, 5 mg Roth CAS 175414-77-4
Voreloxin, min. 95 %, 10 mg Roth CAS 175414-77-4
Voreloxin, min. 95 %, 25 mg Roth CAS 175414-77-4