XL184, 100 mg

cas: 849217-68-1 — see every product listed under this CAS number, including other names

XL184, 100 mg (CAS 849217-68-1) is a chemical reagent available from Chemat. Available pack sizes: 100mg. Offered by: Roth.

brandRoth
catalog numberROTH-2KTK.3
cas849217-68-1
size100mg
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Available pack sizes

brand size price
Roth 100mg 967.52 Pln

properties

delivery time2 week

Cabozantinib is a dicarboxylic acid diamide that is N-phenyl-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide in which the hydrogen at position 4 on the phenyl ring is substituted by a (6,7-dimethoxyquinolin-4-yl)oxy group. A multi-tyrosine kinase inhibitor, used (as its malate salt) for the treatment of progressive, metastatic, medullary thyroid cancer. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It is a member of quinolines, an aromatic ether, a dicarboxylic acid diamide and an organofluorine compound.

Source: ChEBI

Identity
Molecular formulaC28H24FN3O5
Molecular weight501.5 g/mol
IUPAC name1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
InChIKeyONIQOQHATWINJY-UHFFFAOYSA-N
SMILESCOC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F

Computed by PubChem (NCBI)

Synonyms: Cabozantinib, cabozantinibum, Cometriq, Cabozantinib (XL184, BMS-907351), Cabozantinib (BMS-907351), Cabozantinib [USAN], Cabozantinib (USAN), Cabometyx (TN), Cometriq (TN), Cabozantinib [USAN:INN]
Related forms of this compound
1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(2,3,5,6-tetradeuterio-4-fluorophenyl)cyclopropane-1,1-dicarboxamide C28H24FN3O5
1-N-[4-[6,7-bis(trideuteriomethoxy)quinolin-4-yl]oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide C28H24FN3O5

Also listed as

Cabozantinib Chemat Brand CAS 849217-68-1
XL184, >95% (HPLC) TRC CAS 849217-68-1
Cabozantinib/ 99.88% (existing batch purity) TargetMol CAS 849217-68-1
Cabozantinib (XL184, BMS–907351) GLPBio CAS 849217-68-1
XL184 Biosynth CAS 849217-68-1
Cabozantinib 98% Ambeed CAS 849217-68-1
N'-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide, 98%, 98% Chemat CAS 849217-68-1
XL184, 250 mg Roth CAS 849217-68-1
XL184, 500 mg Roth CAS 849217-68-1
Cabozantinib (Standard), 99.33% MedChemExpress CAS 849217-68-1
Cabozantinib, 99.96% MedChemExpress CAS 849217-68-1

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