Products 849217-68-1

CAS 849217-68-1 appears in our catalog under these names: Cabozantinib, XL184, >95% (HPLC), Cabozantinib/ 99.88% (existing batch purity), Cabozantinib (XL184, BMS–907351), XL184. Offered by: Chemat Brand, TRC, TargetMol, GLPBio, Biosynth. Available pack sizes: on request, 1g, 250mg, 500mg, 5mg, 10mg, 50mg, 100mg.

Cabozantinib
Chemat Brand, Chemat, HPC Standards
  • size: on request, 10mg, 50mg, 1x10mg
  • Variants: 5
from 1310.44
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XL184, >95% (HPLC)
TRC
  • size: 1g, 250mg, 500mg
  • Variants: 3
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Cabozantinib/ 99.88% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 50mg, 100mg
  • Variants: 6
from 445.96
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Cabozantinib (XL184, BMS–907351)
GLPBio
  • size: 100mg, 25mg, 5mg, 10mM (in 1ml dmso)
  • Variants: 4
from 742.14
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XL184
Biosynth
  • size: 250mg, 100mg, 500mg, 1000mg
  • Variants: 5
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Cabozantinib 98%
Ambeed
  • size: 1mg, 100mg, 250mg, 1g
  • Variants: 6
from 120.06
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N'-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide, 98%, 98%
Chemat
  • size: 100mg, 250mg, 1g, 5g
  • Variants: 6
from 98.00
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XL184, 100 mg
Roth
  • size: 100mg
  • Variants: 1
from 967.52
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XL184, 250 mg
Roth
  • size: 250mg
  • Variants: 1
from 1628.27
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XL184, 500 mg
Roth
  • size: 500mg
  • Variants: 1
from 2591.06
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Cabozantinib (Standard), 99.33%
MedChemExpress
  • size: 100 mg, 10 mg, 50 mg, 5 mg
  • Variants: 5
from 598.33
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Cabozantinib, 99.96%
MedChemExpress
  • size: 10 mg, 50 mg, 100 mg, 5 mg
  • Variants: 7
from 361.49
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Cabozantinib is a dicarboxylic acid diamide that is N-phenyl-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide in which the hydrogen at position 4 on the phenyl ring is substituted by a (6,7-dimethoxyquinolin-4-yl)oxy group. A multi-tyrosine kinase inhibitor, used (as its malate salt) for the treatment of progressive, metastatic, medullary thyroid cancer. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It is a member of quinolines, an aromatic ether, a dicarboxylic acid diamide and an organofluorine compound.

Source: ChEBI

Identity
Molecular formulaC28H24FN3O5
Molecular weight501.5 g/mol
IUPAC name1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
InChIKeyONIQOQHATWINJY-UHFFFAOYSA-N
SMILESCOC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F

Computed by PubChem (NCBI)

Synonyms: Cabozantinib, cabozantinibum, Cometriq, Cabozantinib (XL184, BMS-907351), Cabozantinib (BMS-907351), Cabozantinib [USAN], Cabozantinib (USAN), Cabometyx (TN), Cometriq (TN), Cabozantinib [USAN:INN]
Related forms of this compound
1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(2,3,5,6-tetradeuterio-4-fluorophenyl)cyclopropane-1,1-dicarboxamide C28H24FN3O5
1-N-[4-[6,7-bis(trideuteriomethoxy)quinolin-4-yl]oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide C28H24FN3O5