Z-DEVD-FMK Caspase-3 Inhibitor

cas: 634911-78-7 — see every product listed under this CAS number, including other names

Z-DEVD-FMK Caspase-3 Inhibitor (CAS 634911-78-7) is a chemical reagent available from Chemat. Available pack sizes: 1mg. Offered by: TargetMol.

brandTargetMol
catalog numberT83963-1mg
cas634911-78-7
size1mg
Need more information?

Ask us about this product — we're happy to help.

Available pack sizes

brand size price
TargetMol 1mg 6887.32 Pln

properties

purityNo data
delivery timeon request
Structural formula: {0} (CAS {1})

Z-DEVD-FMK is a tetrapeptide consisting of Fmoc-L-aspartic acid 4-methyl ester, methyl L-alpha-glutamic acid 5-methyl ester, L-valine and the fluoromethyl ketone derived from the 1-carboxy group of L-aspartic acid 4-methyl ester coupled in sequence. It is a specific, irreversible caspase-3 inhibitor that also shows potent inhibition of caspase-6, caspase-7, caspase-8, and caspase-10. It has a role as an EC 3.4.22.56 (caspase-3) inhibitor, a neuroprotective agent and an apoptosis inhibitor.

Source: ChEBI

Identity
Molecular formulaC30H41FN4O12
Molecular weight668.7 g/mol
IUPAC namemethyl (4S)-5-[[(2S)-1-[[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-[[(2S)-4-methoxy-4-oxo-2-(phenylmethoxycarbonylamino)butanoyl]amino]-5-oxopentanoate
InChIKeyGBJVAVGBSGRRKN-JYEBCORGSA-N
SMILESCC(C)[C@@H](C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)[C@H](CCC(=O)OC)NC(=O)[C@H](CC(=O)OC)NC(=O)OCC1=CC=CC=C1

Computed by PubChem (NCBI)

Synonyms: Z-DEVD-FMK, benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone, N-benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethyl ketone, benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone, Z-Asp-Glu-Val-Asp-fluoromethyl ketone, Caspase-3 Inhibitor, Z-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone, Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-Fluoromethylketone, Z-D(OMe)E(Ome)VD(OMe)-FMK, Z-DEVD-fluoromethylketone
Related forms of this compound
methyl (4S)-5-[[(2S)-1-[[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-[[(2S)-4-methoxy-4-oxo-2-(phenylmethoxycarbonylamino)butanoyl]amino]-5-oxopentanoate C30H41FN4O12

Also listed as

Z–Asp(OMe)–Glu(OMe)–Val–DL–Asp(OMe)–fluoromethylketone GLPBio CAS 634911-78-7