ZM 447439
cas: 331771-20-1 — see every product listed under this CAS number, including other names
ZM 447439 (CAS 331771-20-1) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 25mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: TRC, GLPBio.
| brand | TRC |
|---|---|
| catalog number | TRC-Z487000-10MG |
| cas | 331771-20-1 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| TRC | 10mg | price on request | |
| GLPBio | 10mg | 681.29 Pln | |
| GLPBio | 25mg | 938.72 Pln | |
| GLPBio | 5mg | 550.23 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 639.16 Pln | |
| GLPBio | 50mg | 1308.48 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
ZM447439 is a member of the class of quinazolines that is quinazoline which is substituted at positions 4, 6 and 7 by a (4-benzamidophenyl)nitrilo group, methoxy group and a 3-(morpholin-4-yl)propoxy group, respectively. It is an ATP-competitive inhibitor of Aurora A and Aurora B kinases with IC50 of 110 nM and 130 nM, respectively. It has a role as an antineoplastic agent, an apoptosis inducer and an Aurora kinase inhibitor. It is a member of benzamides, an aromatic ether, a member of quinazolines, a member of morpholines, a polyether, a secondary amino compound and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C29H31N5O4 |
|---|---|
| Molecular weight | 513.6 g/mol |
| IUPAC name | N-[4-[[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino]phenyl]benzamide |
| InChIKey | OGNYUTNQZVRGMN-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)NC(=O)C4=CC=CC=C4)OCCCN5CCOCC5 |
Computed by PubChem (NCBI)
Synonyms:
4-(4-(n-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)quinazoline, N-(4-((6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-yl)amino)phenyl)benzamide, N-[4-[[6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-yl]amino]phenyl]benzamide, OGNYUTNQZVRGMN-UHFFFAOYSA-N, Kinome_3319, orb1301094, s1103