Products 331771-20-1

CAS 331771-20-1 appears in our catalog under these names: ZM 447439, ZM 447439, ZM-447439/ 98.53% (existing batch purity), ZM-447439 98%, Aurora Kinase Inhibitor VI, 1PC X 5MG. Offered by: TRC, GLPBio, TargetMol, Ambeed, Sigma-Aldrich. Available pack sizes: 10mg, 25mg, 5mg, 10mM (in 1ml dmso), 50mg, 100mg, 1mg, 250mg.

ZM 447439
TRC
  • size: 10mg
  • Variants: 1
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ZM 447439
GLPBio
  • size: 10mg, 25mg, 5mg, 10mM (in 1ml dmso)
  • Variants: 5
from 550.23
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ZM-447439/ 98.53% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 50mg, 100mg
  • Variants: 4
from 478.94
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ZM-447439 98%
Ambeed
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 7
from 225.75
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Aurora Kinase Inhibitor VI, 1PC X 5MG
Sigma-Aldrich
  • size: 5MG
  • Variants: 1
from 876.00
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ZM447439, 98%, 98%
Chemat
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 5
from 131.60
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ZM-447439, 99.19%
MedChemExpress
  • size: 100 mg, 10 mg, 25 mg, 10mM/1mL
  • Variants: 6
from 407.93
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ZM-447439 (Standard)
MedChemExpress
  • size: Get quote
  • Variants: 1
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N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide, 98%
Fluorochem
  • size: 10mg, 50mg
  • Variants: 2
from 513.38
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Structural formula: {0} (CAS {1})

ZM447439 is a member of the class of quinazolines that is quinazoline which is substituted at positions 4, 6 and 7 by a (4-benzamidophenyl)nitrilo group, methoxy group and a 3-(morpholin-4-yl)propoxy group, respectively. It is an ATP-competitive inhibitor of Aurora A and Aurora B kinases with IC50 of 110 nM and 130 nM, respectively. It has a role as an antineoplastic agent, an apoptosis inducer and an Aurora kinase inhibitor. It is a member of benzamides, an aromatic ether, a member of quinazolines, a member of morpholines, a polyether, a secondary amino compound and a tertiary amino compound.

Source: ChEBI

Identity
Molecular formulaC29H31N5O4
Molecular weight513.6 g/mol
IUPAC nameN-[4-[[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino]phenyl]benzamide
InChIKeyOGNYUTNQZVRGMN-UHFFFAOYSA-N
SMILESCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)NC(=O)C4=CC=CC=C4)OCCCN5CCOCC5

Computed by PubChem (NCBI)

Synonyms: 4-(4-(n-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)quinazoline, N-(4-((6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-yl)amino)phenyl)benzamide, N-[4-[[6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-yl]amino]phenyl]benzamide, OGNYUTNQZVRGMN-UHFFFAOYSA-N, Kinome_3319, orb1301094, s1103