Products 1001350-96-4
CAS 1001350-96-4 appears in our catalog under these names: BMS 754807, min. 95 %, 100 mg, BMS 754807, BMS-754807/ 98.86% (existing batch purity), BMS–754807, BMS-754807 98+%. Offered by: Roth, Chemat Brand, TargetMol, GLPBio, Biosynth. Available pack sizes: 100mg, on request, 1mg, 2mg, 5mg, 10mg, 25mg, 50mg.
BMS-754807 is a pyrrolotriazine that is pyrrolo[2,1-f][1,2,4]triazine which is substituted at position 2 by the pyrrolidine nitrogen of (2S)-N-(6-fluoropyridin-3-yl)-2-methylprolinamide, and at position 4 by a (5-cyclopropyl-1H-pyrazol-3-yl)amino group. It is a potent, reversible inhibitor of the insulin-like growth factor 1 receptor/insulin receptor family kinases. It has a role as an antineoplastic agent and an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is a member of pyrazoles, a member of pyridines, a member of pyrrolidines and a pyrrolotriazine.
Source: ChEBI
| Molecular formula | C23H24FN9O |
|---|---|
| Molecular weight | 461.5 g/mol |
| IUPAC name | (2S)-1-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridinyl)-2-methylpyrrolidine-2-carboxamide |
| InChIKey | LQVXSNNAFNGRAH-QHCPKHFHSA-N |
| SMILES | C[C@]1(CCCN1C2=NN3C=CC=C3C(=N2)NC4=NNC(=C4)C5CC5)C(=O)NC6=CN=C(C=C6)F |
Computed by PubChem (NCBI)