Products 1025967-78-5

CAS 1025967-78-5 appears in our catalog under these names: Lifitegrast, Lifitegrast, >95% (HPLC), Lifitegrast/ 99.4% (existing batch purity), Lifitegrast 97%, (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid, 97%, 97%. Offered by: GLPBio, Chemat Brand, TRC, Mikromol, TargetMol. Available pack sizes: 5mg, on request, 10mg, 250mg, 25mg, 50mg, 100mg, 500mg.

Lifitegrast
GLPBio, Chemat Brand, Mikromol
  • size: 5mg, on request, 250mg, 1mg
  • Variants: 10
from 545.55
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Lifitegrast, >95% (HPLC)
TRC
  • size: 10mg, 250mg, 5mg
  • Variants: 3
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Lifitegrast/ 99.4% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 6
from 405.71
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Lifitegrast 97%
Ambeed
  • size: 1mg, 5mg, 25mg, 50mg
  • Variants: 8
from 175.69
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(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid, 97%, 97%
Chemat
  • size: 10mg, 25mg, 50mg, 100mg
  • Variants: 6
from 122.00
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Lifitegrast, 99.29%
MedChemExpress
  • size: 10 mg, 50 mg, 25 mg, 100 mg
  • Variants: 7
from 319.69
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Lifitegrast (Standard)
MedChemExpress
  • size: 50 mg, 100 mg, 10 mg, 25 mg
  • Variants: 5
from 621.55
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LIFITEGRAST, 97%
Fluorochem
  • size: 25mg, 50mg, 100mg, 250mg
  • Variants: 5
from 227.02
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Lifitegrast-d4
Chemat Brand
  • size: on request
  • Variants: 1
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Structural formula: {0} (CAS {1})

Lifitegrast is an N-acyl-L-alpha-amino acid obtained by formal condensation of the carboxy group of N-[2-(1-benzofuran-6-carbonyl)]-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid with the amino group of 3-(methanesulfonyl)-L-phenylalanine. Used for treatment of keratoconjunctivitis sicca (dry eye syndrome). It has a role as a lymphocyte function-associated antigen-1 antagonist and an anti-inflammatory drug. It is a member of isoquinolines, a sulfone, a member of 1-benzofurans, a N-acyl-L-alpha-amino acid and a L-phenylalanine derivative.

Source: ChEBI

Identity
Molecular formulaC29H24Cl2N2O7S
Molecular weight615.5 g/mol
IUPAC name(2S)-2-[[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-methylsulfonylphenyl)propanoic acid
InChIKeyJFOZKMSJYSPYLN-QHCPKHFHSA-N
SMILESCS(=O)(=O)C1=CC=CC(=C1)C[C@@H](C(=O)O)NC(=O)C2=C(C=C3CN(CCC3=C2Cl)C(=O)C4=CC5=C(C=C4)C=CO5)Cl

Computed by PubChem (NCBI)

Synonyms: Lifitegrast, Xiidra, lifitegrastum, Lifitegrast(SAR 1118), Lifitegrast [USAN:INN], C29H24Cl2N2O7S, Xiidra (TN), Lifitegrast (Standard), LIFITEGRAST [MI], LIFITEGRAST [INN]
Related forms of this compound
(2R)-2-[[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-methylsulfonylphenyl)propanoic acid C29H24Cl2N2O7S