Products 1032568-63-0

CAS 1032568-63-0 appears in our catalog under these names: Copanlisib, Copanlisib/ 99.88% (existing batch purity), BAY 80–6946 (Copanlisib), Copanlisib 98%, Copanlisib, 99.35%. Offered by: Chemat Brand, TargetMol, GLPBio, Biosynth, Ambeed. Available pack sizes: on request, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg, 5g.

Copanlisib
Chemat Brand, Biosynth
  • size: on request, 25mg, 2mg, 5mg
  • Variants: 5
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Copanlisib/ 99.88% (existing batch purity)
TargetMol
  • size: 2mg, 5mg, 10mg, 25mg
  • Variants: 6
from 399.00
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BAY 80–6946 (Copanlisib)
GLPBio
  • size: 10mg, 100mg, 2mg, 5mg
  • Variants: 5
from 662.57
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Copanlisib 98%
Ambeed
  • size: 5g, 2mg, 5mg, 10mg
  • Variants: 9
from 147.88
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Copanlisib, 99.35%
MedChemExpress
  • size: 10 mg, 50 mg, 5 mg, 100 mg
  • Variants: 4
from 407.93
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Copanlisib (Standard)
MedChemExpress
  • size: 100 mg, 25 mg, 10 mg, 5 mg
  • Variants: 5
from 839.82
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2-Amino-N-[2,3-dihydro-7-methoxy-8-[3-(4-morpholinyl)propoxy]imidazo[1,2-c]quinazolin-5-yl]-5-pyrimidinecarboxamide, 98%, 98%
Chemat
  • size: 2mg, 5mg, 10mg, 25mg
  • Variants: 8
from 98.00
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Structural formula: {0} (CAS {1})

Copanlisib is an imidazoquinazoline that is 2,3-dihydroimidazo[1,2-c]quinazoline substituted by (2-aminopyrimidine-5-carbonyl)amino, methoxy, and 3-(morpholin-4-yl)propoxy groups at positions 5, 7 and 8, respectively. It is a intravenous pan-class I PI3K inhibitor used for the treatment of relapsed follicular lymphoma in patients who have received at least 2 prior systemic therapies. It has a role as an antineoplastic agent, an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor and an apoptosis inducer. It is a secondary carboxamide, an aromatic ether, an aminopyrimidine, a member of morpholines, a diether, an imidazoquinazoline, a pyrimidinecarboxamide and a tertiary amino compound.

Source: ChEBI

Identity
Molecular formulaC23H28N8O4
Molecular weight480.5 g/mol
IUPAC name2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydro-1H-imidazo[1,2-c]quinazolin-5-ylidene]pyrimidine-5-carboxamide
InChIKeyMWYDSXOGIBMAET-UHFFFAOYSA-N
SMILESCOC1=C(C=CC2=C3NCCN3C(=NC(=O)C4=CN=C(N=C4)N)N=C21)OCCCN5CCOCC5

Computed by PubChem (NCBI)

Synonyms: Copanlisib, Aliqopa, Copanlisib [USAN:INN], COPANLISIB [USAN], Copanlisib (BAY 80-6946), s2802, Copanlisib [INN], copanlisibum, Copanlisib tris-HCl, Copanlisib (Standard)
Related forms of this compound
2-amino-N-[7-methoxy-8-[3-(2,2,3,3,5,5,6,6-octadeuteriomorpholin-4-yl)propoxy]-2,3-dihydro-1H-imidazo[1,2-c]quinazolin-5-ylidene]pyrimidine-5-carboxamide C23H28N8O4