Products 1051375-10-0
CAS 1051375-10-0 appears in our catalog under these names: Cabotegravir, min. 95 %, 10 mg, GSK744 (S/GSK1265744), Cabotegravir, Cabotegravir, >95% (HPLC), Cabotegravir/ 99.92% (existing batch purity). Offered by: Roth, GLPBio, Chemat Brand, TRC, TargetMol. Available pack sizes: 10mg, on request, 25mg, 5mg, 50mg, 100mg, 10mM (in 1ml dmso), 250mg.
Cabotegravir is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of (3S,11aR)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydro[1,3]oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxylic acid with the amino group of 2,4-difluorobenzylamine. Used (as its sodium salt) for treatment of HIV-1. It has a role as a HIV-1 integrase inhibitor. It is a secondary carboxamide, an organic heterotricyclic compound, a monocarboxylic acid amide and a difluorobenzene. It is a conjugate acid of a cabotegravir(1-).
Source: ChEBI
| Molecular formula | C19H17F2N3O5 |
|---|---|
| Molecular weight | 405.4 g/mol |
| IUPAC name | (3R,6S)-N-[(2,4-difluorophenyl)methyl]-10-hydroxy-6-methyl-8,11-dioxo-4-oxa-1,7-diazatricyclo[7.4.0.03,7]trideca-9,12-diene-12-carboxamide |
| InChIKey | WCWSTNLSLKSJPK-LKFCYVNXSA-N |
| SMILES | C[C@H]1CO[C@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O |
Computed by PubChem (NCBI)