Products 1067286-75-2

CAS 1067286-75-2 is the registry number for TOPOTECAN HYDROCHLORIDE, UNITED STATES P. Offered by: Sigma-Aldrich. Available pack sizes: 350MG.

TOPOTECAN HYDROCHLORIDE, UNITED STATES P
Sigma-Aldrich
  • size: 350MG
  • Variants: 1
from 2430.00
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Structural formula: {0} (CAS {1})

Topotecan hydrochloride is a pyranoindolizinoquinoline. It has a role as an antineoplastic agent and an EC 5.99.1.2 (DNA topoisomerase) inhibitor. It contains a topotecan.

Source: ChEBI

Identity
Molecular formulaC23H24ClN3O5
Molecular weight457.9 g/mol
IUPAC name(19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride
InChIKeyDGHHQBMTXTWTJV-BQAIUKQQSA-N
SMILESCC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O.Cl

Computed by PubChem (NCBI)

Synonyms: TOPOTECAN HYDROCHLORIDE, Topotecan Hcl, Nogitecan hydrochloride, Evotopin, Topotecan teva, Topotecan Actavis, Topotecan Hospira, potactasol, Topotecan (as hydrochloride), Hydrochloride, Nogitecan
Related forms of this compound
(19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride C23H24ClN3O5
(19S)-8-[[bis(trideuteriomethyl)amino]methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride C23H24ClN3O5
Isomers (same molecular formula)
5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazole-3-carboxamide C23H24ClN3O5
5-chloro-N-[(2S,3R)-4-[(3S,4R)-3,4-dihydroxypyrrolidin-1-yl]-3-hydroxy-4-oxo-1-phenylbutan-2-yl]-1H-indole-2-carboxamide C23H24ClN3O5