Products 106941-25-7
CAS 106941-25-7 appears in our catalog under these names: Adefovir, Adefovir, 97%, Adefovir, >95% (HPLC), Adefovir - Bio-X â„¢, Adefovir, >98.0%(HPLC)(T). Offered by: GLPBio, Combi-blocks, Chemat Brand, TRC, Biosynth. Available pack sizes: 25mg, 25g, 500g, 5g, 100g, 1g, on request, 100mg.
Adefovir is a member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens has been replaced by a 2-(6-amino-9H-purin-9-yl)ethoxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(t-butoxycarbonyloxymethyl) ester (dipivoxil ester) prodrug is used to treat chronic hepatitis B viral infection. It has a role as an antiviral drug, a drug metabolite, a nephrotoxic agent, a HIV-1 reverse transcriptase inhibitor and a DNA synthesis inhibitor. It is a member of 6-aminopurines, an ether and a member of phosphonic acids. It is functionally related to an adenine. It is a conjugate acid of an adefovir(1-).
Source: ChEBI
| Molecular formula | C8H12N5O4P |
|---|---|
| Molecular weight | 273.19 g/mol |
| IUPAC name | 2-(6-aminopurin-9-yl)ethoxymethylphosphonic acid |
| InChIKey | SUPKOOSCJHTBAH-UHFFFAOYSA-N |
| SMILES | C1=NC(=C2C(=N1)N(C=N2)CCOCP(=O)(O)O)N |
Computed by PubChem (NCBI)
Synonyms:
ADEFOVIR, ((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid, PMEA, 9-(2-Phosphonylmethoxyethyl)adenine, 9-(2-(Phosphonomethoxy)ethyl)adenine, 2-(6-aminopurin-9-yl)ethoxymethylphosphonic acid, N-(2-Phosphonylmethoxyethyl)adenine, {[2-(6-Amino-9h-Purin-9-Yl)ethoxy]methyl}phosphonic Acid, 9-(2-phosphonomethoxyethyl)adenine, Phosphonic acid, [[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-