Products 117414-74-1

CAS 117414-74-1 appears in our catalog under these names: D-CPP-ene, D–CPP–ene, Midafotel, 99.00%. Offered by: TRC, GLPBio, MedChemExpress. Available pack sizes: 250mg, 10mg, 5 mg, 1 mg.

D-CPP-ene
TRC
  • size: 250mg
  • Variants: 1
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D–CPP–ene
GLPBio
  • size: 10mg
  • Variants: 1
from 2974.73
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Midafotel, 99.00%
MedChemExpress
  • size: 5 mg, 1 mg
  • Variants: 2
from 1271.71
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Structural formula: {0} (CAS {1})

Midafotel is a member of the class of piperazines that is piperazine substituted by a carboxy group at position 2R and a (1E)-1-phosphonoprop-1-en-3-yl group at position 4. It is an antagonist of N-methyl-D-aspartate receptors (NMDARs) and was in clinical development by Novartis for the treatment of cognition disorders and brain injuries (now discontinued). It has a role as an anticonvulsant, a NMDA receptor antagonist and a neuroprotective agent. It is a monocarboxylic acid, a member of phosphonic acids, a piperazinecarboxylic acid, a tertiary amino compound and an olefinic compound.

Source: ChEBI

Identity
Molecular formulaC8H15N2O5P
Molecular weight250.19 g/mol
IUPAC name(2R)-4-[(E)-3-phosphonoprop-2-enyl]piperazine-2-carboxylic acid
InChIKeyVZXMZMJSGLFKQI-ABVWVHJUSA-N
SMILESC1CN(C[C@@H](N1)C(=O)O)C/C=C/P(=O)(O)O

Computed by PubChem (NCBI)

Synonyms: Midafotel, D-Cpp-ene, d-cppene, Midafotel [INN], midafotelum, D(-)CPPene, (R)-CPP-ene, MIDAFOTEL [WHO-DD], (2R)-4-[(2E)-3-phosphonoprop-2-en-1-yl]piperazine-2-carboxylic acid, (R)-4-[(E)-3-phosphonoprop-2-enyl]piperazine-2-carboxylic acid