Products 1191995-00-2

CAS 1191995-00-2 appears in our catalog under these names: Dorzagliatin/ 99.74% (existing batch purity), Dorzagliatin, Dorzagliatin 99%, Dorzagliatin, 99%, 99%, Dorzagliatin, 99.89%. Offered by: TargetMol, GLPBio, Biosynth, Ambeed, Chemat. Available pack sizes: 1mg, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg, 10mM (in 1ml dmso).

Dorzagliatin/ 99.74% (existing batch purity)
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 7
from 412.42
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Dorzagliatin
GLPBio, Biosynth
  • size: 1mg, 10mg, 100mg, 25mg
  • Variants: 9
from 587.68
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Dorzagliatin 99%
Ambeed
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 8
from 197.94
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Dorzagliatin, 99%, 99%
Chemat
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 8
from 170.00
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Dorzagliatin, 99.89%
MedChemExpress
  • size: 10mM/1mL, 25 mg, 5 mg, 10 mg
  • Variants: 6
from 593.69
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Dorzagliatin (Standard), 98.47%
MedChemExpress
  • size: 25 mg, 100 mg, 50 mg, 10 mg
  • Variants: 5
from 1545.71
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Structural formula: {0} (CAS {1})

Dorzagliatin is a secondary carboxamide resulting from the formal condensation of the carboxy group of (2S)-2-[4-(2-chlorophenoxy)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl]-4-methylpentanoic acid with the amino group of (2R)-3-(3-amino-1H-pyrrol-1-yl)propane-1,2-diol. It is an allosteric glucokinase activator developed by Hua Medicine for the treatment of type 1 and 2 diabetes mellitus , and diabetic kidney disease. It has a role as an enzyme activator and a hypoglycemic agent. It is a secondary carboxamide, a primary alcohol, a pyrroline, a diol, a member of pyrazoles, an aromatic ether, a secondary alcohol, a tertiary amino compound, an enone and a member of monochlorobenzenes.

Source: ChEBI

Identity
Molecular formulaC22H27ClN4O5
Molecular weight462.9 g/mol
IUPAC name(2S)-2-[3-(2-chlorophenoxy)-5-oxo-2H-pyrrol-1-yl]-N-[1-[(2R)-2,3-dihydroxypropyl]pyrazol-3-yl]-4-methylpentanamide
InChIKeyHMUMWSORCUWQJO-QAPCUYQASA-N
SMILESCC(C)C[C@@H](C(=O)NC1=NN(C=C1)C[C@H](CO)O)N2CC(=CC2=O)OC3=CC=CC=C3Cl

Computed by PubChem (NCBI)

Synonyms: Dorzagliatin, Sinogliatin, dorzagliatina, dorzagliatine, dorzagliatinum, Dorzagliatin [INN], Dorzagliatin (USAN), DORZAGLIATIN [USAN], Dorzagliatin?, HuaTangNing
Related forms of this compound
(2S)-2-[3-(2-chlorophenoxy)-5-oxo-2H-pyrrol-1-yl]-N-[1-[(2S)-2,3-dihydroxypropyl]pyrazol-3-yl]-4-methylpentanamide C22H27ClN4O5