Products 1195765-45-7

CAS 1195765-45-7 appears in our catalog under these names: Dabrafenib, Dabrafenib, >95% (HPLC), Dabrafenib/ 99.83% (existing batch purity), Dabrafenib (GSK2118436), Dabrafenib 98%. Offered by: Chemat Brand, TRC, TargetMol, GLPBio, Biosynth. Available pack sizes: on request, 10mg, 25mg, 50mg, 5mg, 100mg, 200mg, 10mM (in 1ml dmso).

Dabrafenib
Chemat Brand, Biosynth
  • size: on request, 50mg, 25mg, 100mg
  • Variants: 6
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Dabrafenib, >95% (HPLC)
TRC
  • size: 10mg, 25mg, 50mg
  • Variants: 3
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Dabrafenib/ 99.83% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 6
from 452.11
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Dabrafenib (GSK2118436)
GLPBio
  • size: 10mg, 100mg, 10mM (in 1ml dmso), 50mg
  • Variants: 4
from 611.08
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Dabrafenib 98%
Ambeed
  • size: 1mg, 5mg, 50mg, 100mg
  • Variants: 8
from 120.06
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N-[3-[5-(2-Amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide, 98%, 98%
Chemat
  • size: 5mg, 100mg, 250mg, 1g
  • Variants: 6
from 78.80
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Dabrafenib, 99.97%
MedChemExpress
  • size: 100 mg, 500 mg, 200 mg, 10 mg
  • Variants: 8
from 361.49
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Dabrafenib (Standard)
MedChemExpress
  • size: 100 mg, 25 mg, 50 mg, 5 mg
  • Variants: 5
from 719.08
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Dabrafenib is an organofluorine compound and antineoplastic agent, used as its mesylate salt in treatment of metastatic melanoma. It has a role as an anticoronaviral agent, an antineoplastic agent and a B-Raf inhibitor. It is a sulfonamide, an organofluorine compound, an aminopyrimidine and a member of 1,3-thiazoles.

Source: ChEBI

Identity
Molecular formulaC23H20F3N5O2S2
Molecular weight519.6 g/mol
IUPAC nameN-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide
InChIKeyBFSMGDJOXZAERB-UHFFFAOYSA-N
SMILESCC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F

Computed by PubChem (NCBI)

Synonyms: Dabrafenib, dabrafenibum, BRAF Inhibitor GSK2118436, Tafinlar, Dabrafenib (GSK2118436), Dabrafenib (Free Base), DABRAFENIB [MI], Dabrafenib (USAN), DABRAFENIB [USAN], Dabrafenib [USAN:INN]
Related forms of this compound
N-[3-[5-(2-aminopyrimidin-4-yl)-2-[1,1,1,3,3,3-hexadeuterio-2-(trideuteriomethyl)propan-2-yl]-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide C23H20F3N5O2S2