Products 1225497-78-8

CAS 1225497-78-8 appears in our catalog under these names: ON-01910 Sodium Salt, Rigosertib (ON–01910,Estybon), (E/Z)-Rigosertib sodium/ 99.11% (existing batch purity), Rigosertib, (E/Z)-Rigosertib sodium 98% （E）. Offered by: TRC, GLPBio, TargetMol, Biosynth, Ambeed. Available pack sizes: 100mg, 25mg, 5mg, 10mM (in 1ml dmso), 2mg, 10mg, 50mg, 250mg.

ON-01910 Sodium Salt
TRC
  • size: 100mg, 25mg, 5mg
  • Variants: 3
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Rigosertib (ON–01910,Estybon)
GLPBio
  • size: 100mg, 25mg, 5mg, 10mM (in 1ml dmso)
  • Variants: 4
from 821.70
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(E/Z)-Rigosertib sodium/ 99.11% (existing batch purity)
TargetMol
  • size: 2mg, 5mg, 10mg, 25mg
  • Variants: 6
from 412.42
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Rigosertib
Biosynth
  • size: 10mg, 5mg, 25mg
  • Variants: 3
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(E/Z)-Rigosertib sodium 98% （E）
Ambeed
  • size: 250mg, 1mg, 5mg, 10mg
  • Variants: 7
from 175.69
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Rigosertib Sodium(Random Configuration), 98% （E）, 98% （E）
Chemat
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 8
from 98.00
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(E/Z)-Rigosertib (sodium)
MedChemExpress
  • size: 10 mg, 100 mg, 5 mg, 50 mg
  • Variants: 5
from 245.39
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Structural formula: {0} (CAS {1})

Rigosertib sodium is the sodium salt of rigosertib. It is an anti-cancer agent which has been granted Orphan Drug Designation by the FDA for use in patients with myelodysplastic syndromes (MDS). It has a role as an EC 2.7.11.21 (polo kinase) inhibitor, an antineoplastic agent, a microtubule-destabilising agent and an apoptosis inducer. It contains a rigosertib(1-).

Source: ChEBI

Identity
Molecular formulaC21H24NNaO8S
Molecular weight473.5 g/mol
IUPAC namesodium 2-[2-methoxy-5-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]anilino]acetate
InChIKeyVLQLUZFVFXYXQE-USRGLUTNSA-M
SMILESCOC1=C(C=C(C=C1)CS(=O)(=O)/C=C/C2=C(C=C(C=C2OC)OC)OC)NCC(=O)[O-].[Na+]

Computed by PubChem (NCBI)

Synonyms: Rigosertib sodium, Estybon, Novonex, SyB C-1101, Polo-like kinase 1 Inhibitor ON 01910.Na, Rigosertib sodium [USAN], Rigosertib (ON-01910), Rigosertib Sodium(Random Configuration), (E/Z)-Rigosertib (sodium), Rigosertib-d6