CAS 124236-29-9 appears in our catalog under these names: trans-Crotamiton, >95% (HPLC), trans-Crotamiton, N-Ethyl-o-crotonotoluidide, >95.0%(GC), N-Ethyl-o-crotonotoluidide 98%, (2E)-N-Ethyl-N-(2-methylphenyl)-2-butenamide, 98%, 98%. Offered by: TRC, Biosynth, TCI, Ambeed, Chemat. Available pack sizes: 1g, 25g, 5g, 20g, 10g, 100g.
Crotamiton is an enamide resulting from the formal condensation of crotonic acid with N-ethyl-2-methylaniline. A colourless or pale yellow oily liquid, it is used in the treatment of pruritus (itching) by producing a counter-irritation: as it evaporates from the skin, it produces a cooling effect that diverts attention away from the itching. It has also been used as an acaricide in the treatment of scabies, though more effective drugs are usually preferred. It has a role as an antipruritic drug and a scabicide. It is a tertiary carboxamide and an enamide.
Source: ChEBI
| Molecular formula | C13H17NO |
|---|---|
| Molecular weight | 203.28 g/mol |
| IUPAC name | (E)-N-ethyl-N-(2-methylphenyl)but-2-enamide |
| InChIKey | DNTGGZPQPQTDQF-XBXARRHUSA-N |
| SMILES | CCN(C1=CC=CC=C1C)C(=O)/C=C/C |
Computed by PubChem (NCBI)