Products 1245537-68-1

CAS 1245537-68-1 appears in our catalog under these names: 2H-Imidazo[4,5-c]quinolin-2-one,1,3-dihydro-8-(6-methoxy-3-pyridinyl)-3-methyl-1-[4-(1-piperazinyl)-3-(trifluoromethyl)phenyl]- (2Z)-2-butenedioate (1:1), 99%, 99%, BGT 226, >95% (HPLC), BGT226 maleate/ 98.78% (existing batch purity), NVP–BGT226, NVP BGT 226. Offered by: Chemat, TRC, TargetMol, GLPBio, Biosynth. Available pack sizes: 25mg, 50mg, 100mg, 5mg, 1mg, 10mg, 500mg, 10mM (in 1ml dmso).

2H-Imidazo[4,5-c]quinolin-2-one,1,3-dihydro-8-(6-methoxy-3-pyridinyl)-3-methyl-1-[4-(1-piperazinyl)-3-(trifluoromethyl)phenyl]- (2Z)-2-butenedioate (1:1), 99%, 99%
Chemat
  • size: 25mg, 50mg, 100mg
  • Variants: 3
from 506.00
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BGT 226, >95% (HPLC)
TRC
  • size: 50mg, 5mg
  • Variants: 2
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BGT226 maleate/ 98.78% (existing batch purity)
TargetMol
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 7
from 538.75
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NVP–BGT226
GLPBio
  • size: 10mg, 5mg, 10mM (in 1ml dmso), 50mg
  • Variants: 4
from 957.44
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NVP BGT 226
Biosynth
  • size: 10mg, 25mg, 50mg, 100mg
  • Variants: 4
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BGT226 maleate
Chemat
  • size: 10mg, 1mg, 5mg
  • Variants: 3
from 1102.07
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BGT226 (maleate), 99.92%
MedChemExpress
  • size: 10 mg, 50 mg, 25 mg, 10mM/1mL
  • Variants: 7
from 361.49
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Structural formula: {0} (CAS {1})

BGT226 is the maleate salt of 8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl]-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one. A dual PI3K/mTOR inhibitor. It has a role as an antineoplastic agent, an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor and a mTOR inhibitor. It contains a BGT226(1+).

Source: ChEBI

Identity
Molecular formulaC32H29F3N6O6
Molecular weight650.6 g/mol
IUPAC name(Z)-but-2-enedioic acid;8-(6-methoxy-3-pyridinyl)-3-methyl-1-[4-piperazin-1-yl-3-(trifluoromethyl)phenyl]imidazo[4,5-c]quinolin-2-one
InChIKeyYUXMAKUNSXIEKN-BTJKTKAUSA-N
SMILESCN1C2=CN=C3C=CC(=CC3=C2N(C1=O)C4=CC(=C(C=C4)N5CCNCC5)C(F)(F)F)C6=CN=C(C=C6)OC.C(=C\C(=O)O)\C(=O)O

Computed by PubChem (NCBI)

Synonyms: orb1226685, orb1689309, YUXMAKUNSXIEKN-BTJKTKAUSA-N