Products 1245792-67-9

CAS 1245792-67-9 appears in our catalog under these names: Bci-215, 95%, BCI-215/ 98%, BCI–215, BCI-215, 98%, 98%, BCI-215, 99.86%. Offered by: Combi-blocks, TargetMol, GLPBio, Chemat, MedChemExpress. Available pack sizes: 250mg, 100mg, 1mg, 5mg, 10mg, 25mg, 50mg, 10mM (in 1ml dmso).

Bci-215, 95%
Combi-blocks
  • size: 250mg, 100mg
  • Variants: 2
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BCI-215/ 98%
TargetMol
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 6
from 458.82
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BCI–215
GLPBio
  • size: 10mg, 10mM (in 1ml dmso), 5mg, 50mg
  • Variants: 4
from 859.15
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BCI-215, 98%, 98%
Chemat
  • size: 10mg
  • Variants: 1
from 328.40
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BCI-215, 99.86%
MedChemExpress
  • size: 100 mg, 50 mg, 10 mg, 10mM/1mL
  • Variants: 6
from 695.86
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(E)-2-Benzylidene-5-bromo-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one, 98%
Fluorochem
  • size: 10mg
  • Variants: 1
from 539.41
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Structural formula: {0} (CAS {1})

BCI-215 is an aromatic ketone that is 2,3-dihydro-1H-inden-1-one which is substituted at positions 2, 3, and 5 by (E)-benzylidene, cyclohexylamino, and bromine, respectively. A hyperactivator of fibroblast growth factor signaling in transgenic zebrafish that is devoid of developmental toxicity and restores defective MAPK activity caused by overexpression of DUSP1 and DUSP6 in mammalian cells. It has a role as an antineoplastic agent and an apoptosis inducer. It is a member of indanones, an organobromine compound, a secondary amino compound, an enone and an aromatic ketone.

Source: ChEBI

Identity
Molecular formulaC22H22BrNO
Molecular weight396.3 g/mol
IUPAC name(2E)-2-benzylidene-5-bromo-3-(cyclohexylamino)-3H-inden-1-one
InChIKeyJGWQWVVSCQBAFC-DEDYPNTBSA-N
SMILESC1CCC(CC1)NC\2C3=C(C=CC(=C3)Br)C(=O)/C2=C/C4=CC=CC=C4

Computed by PubChem (NCBI)

Synonyms: (E)-2-Benzylidene-5-bromo-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one, C22H22BrNO, (2E)-2-benzylidene-5-bromo-3-(cyclohexylamino)-3H-inden-1-one, (2E)-2-benzylidene-5-bromo-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one, orb1220473, orb1299920, (2E)-2-benzylidene-5-bromo-3-(cyclohexylamino)indan-1-one, (E)-2-Benzylidene-5-bromo-3-cyclohexylamino-indan-1-one, (E)-5-Bromo-3-(cyclohexylamino)-2-phenylmethylene-1-indanone, (2E)-5-Bromo-3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-1H-inden-1-one