Products 1253186-49-0

CAS 1253186-49-0 appears in our catalog under these names: GSK–5498A, 2,6-Difluoro-N-(1-((2-fluoro-6-(trifluoromethyl)phenyl)methyl)-1H-pyrazol-3-yl)benzamide, GSK-5498A, 99.94%, GSK-5498A, 98.14%. Offered by: GLPBio, Biosynth, MedChemExpress, Chemat. Available pack sizes: 10mg, 2mg, 5mg, 10mM (in 1ml dmso), 1mg, 10 mg, 10mM/1mL, 100 mg.

GSK–5498A
GLPBio
  • size: 10mg, 2mg, 5mg, 10mM (in 1ml dmso)
  • Variants: 4
from 1046.37
View product
2,6-Difluoro-N-(1-((2-fluoro-6-(trifluoromethyl)phenyl)methyl)-1H-pyrazol-3-yl)benzamide
Biosynth
  • size: 5mg, 1mg, 10mg
  • Variants: 3
View product
GSK-5498A, 99.94%
MedChemExpress
  • size: 10 mg, 10mM/1mL, 100 mg, 50 mg
  • Variants: 5
from 1559.64
View product
GSK-5498A, 98.14%
Chemat
  • size: 2mg, 5mg, 10mg
  • Variants: 3
from 2546.00
View product
Structural formula: {0} (CAS {1})

GSK-5498A is a member of the class of pyrazoles that is 1H-pyrazole substituted by 2-fluoro-6-(trifluoromethyl)benzyl and (2,6-difluorobenzoyl)amino groups at positions 1 and 3, respectively. It is a inhibitor of Ca2+ release-activated Ca2+ (CRAC) channel and inhibits the release of mast cell mediators and T-cell cytokines in human and rat preparations. It has a role as a calcium channel blocker. It is a secondary carboxamide, a member of pyrazoles, a difluorobenzene and a member of (trifluoromethyl)benzenes.

Source: ChEBI

Identity
Molecular formulaC18H11F6N3O
Molecular weight399.3 g/mol
IUPAC name2,6-difluoro-N-[1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]pyrazol-3-yl]benzamide
InChIKeyAUBGZAJDHUHMAE-UHFFFAOYSA-N
SMILESC1=CC(=C(C(=C1)F)CN2C=CC(=N2)NC(=O)C3=C(C=CC=C3F)F)C(F)(F)F

Computed by PubChem (NCBI)

Synonyms: 2,6-difluoro-N-(1-(2-fluoro-6-(trifluoromethyl)benzyl)-1H-pyrazol-3-yl)benzamide, 2,6-difluoro-N-{1-[2-fluoro-6-(trifluoromethyl)benzyl]-1H-pyrazol-3-yl}benzamide, orb1709548