Products 1256388-51-8

CAS 1256388-51-8 appears in our catalog under these names: Ledipasvir, Ledipasvir, >95% (HPLC), Ledipasvir/ 99.79% (existing batch purity), Ledipasvir 99%, Ledipasvir, 99.69%. Offered by: Chemat Brand, TRC, TargetMol, GLPBio, Biosynth. Available pack sizes: on request, 10mg, 1mg, 50mg, 2mg, 5mg, 25mg, 100mg.

Ledipasvir
Chemat Brand, GLPBio, Biosynth
  • size: on request, 25mg, 5mg, 10mM (in 1ml dmso)
  • Variants: 8
from 929.36
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Ledipasvir, >95% (HPLC)
TRC
  • size: 10mg, 1mg, 50mg
  • Variants: 3
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Ledipasvir/ 99.79% (existing batch purity)
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 8
from 399.00
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Ledipasvir 99%
Ambeed
  • size: 100mg, 250mg, 1g, 5g
  • Variants: 4
from 342.56
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Ledipasvir, 99.69%
MedChemExpress
  • size: 10mM/1mL, 100 mg, 10 mg, 50 mg
  • Variants: 5
from 561.18
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Ledipasvir, 99%, 99%
Chemat
  • size: 100mg, 250mg, 1g, 1mg
  • Variants: 7
from 78.80
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Ledipasvir, min. 95 %, 10 mg
Roth
  • size: 10mg
  • Variants: 1
from 844.81
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Ledipasvir, min. 95 %, 50 mg
Roth
  • size: 50mg
  • Variants: 1
from 2430.60
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Ledipasvir-d6
Hubei YoungXin
  • size: 10mg, 25mg, 50mg, 100mg
  • Variants: 5
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Structural formula: {0} (CAS {1})

Ledipasvir is a benzimidazole derivative that is used in combination with sofosbuvir (under the trade name Harvoni) for the treatment of chronic hepatitis C genotype 1 infection. It has a role as an antiviral drug and a hepatitis C protease inhibitor. It is a member of benzimidazoles, a carbamate ester, a member of fluorenes, a member of imidazoles, an azaspiro compound, a bridged compound, an organofluorine compound, a carboxamide, a N-acylpyrrolidine and a L-valine derivative.

Source: ChEBI

Identity
Molecular formulaC49H54F2N8O6
Molecular weight889.0 g/mol
IUPAC namemethyl N-[(2S)-1-[(6S)-6-[5-[9,9-difluoro-7-[2-[(1R,3S,4S)-2-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]-2-azabicyclo[2.2.1]heptan-3-yl]-3H-benzimidazol-5-yl]fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]heptan-5-yl]-3-methyl-1-oxobutan-2-yl]carbamate
InChIKeyVRTWBAAJJOHBQU-KMWAZVGDSA-N
SMILESCC(C)[C@@H](C(=O)N1CC2(CC2)C[C@H]1C3=NC=C(N3)C4=CC5=C(C=C4)C6=C(C5(F)F)C=C(C=C6)C7=CC8=C(C=C7)N=C(N8)[C@@H]9[C@H]1CC[C@H](C1)N9C(=O)[C@H](C(C)C)NC(=O)OC)NC(=O)OC

Computed by PubChem (NCBI)

Synonyms: Ledipasvir, HARVONI COMPONENT LEDIPASVIR, ledipasvirum, Ledipasvir acetonate, Ledipasvir [USAN:INN], LEDIPASVIR [ORANGE BOOK], LEDIPASVIR ACETONATE [JAN], Ledipasvir [USAN], Ledipasvir?, LedipasvirGS-5885
Related forms of this compound
methyl N-[(2S)-1-[(6S)-6-[5-[9,9-difluoro-7-[2-[(1R,3S,4S)-2-[(2R)-2-(methoxycarbonylamino)-3-methylbutanoyl]-2-azabicyclo[2.2.1]heptan-3-yl]-3H-benzimidazol-5-yl]fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]heptan-5-yl]-3-methyl-1-oxobutan-2-yl]carbamate C49H54F2N8O6
trideuteriomethyl N-[(2S)-1-[(6S)-6-[5-[9,9-difluoro-7-[2-[(1R,3S,4S)-2-[(2S)-3-methyl-2-(trideuteriomethoxycarbonylamino)butanoyl]-2-azabicyclo[2.2.1]heptan-3-yl]-3H-benzimidazol-5-yl]fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]heptan-5-yl]-3-methyl-1-oxobutan-2-yl]carbamate C49H54F2N8O6
Isomers (same molecular formula)
[(2R)-1-[(6S)-6-[5-[9,9-difluoro-7-[2-[(1R,3S,4S)-2-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]-2-azabicyclo[2.2.1]heptan-3-yl]-3H-benzimidazol-5-yl]fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]heptan-5-yl]-3-methyl-1-oxobutan-2-yl]-methylcarbamic acid C49H54F2N8O6